Production of Gel with Menthol, Benzocaine and Procaine HCl for Topical Application in Rheumatoid Arthritis Patients  

作　　者：B. Angelovska S. Maleska- Stoj adinovikj E. Drakalska B. Gjorgjeska 

机构地区：[1]Facutly of medical sciences, University "Goee Delcev "-Stip, Stip 2000, R. Macedonia [2]Public Hospital-Ohrid, R. Macedonia,-"Dimitar Vlahov" Ohrid, 33- 6000, R.Macedonia

出　　处：《Journal of Pharmacy and Pharmacology》2017年第5期245-248,共4页药剂与药理学（英文版）

摘　　要：Antirheurnatic and analgesics drugs are the most commonly prescribed medications for treatment of acute and chronic pain. Frequent application of these agents often causes adverse effects. So, in order to avoid the incidence of side effects, topical analgesics are treatment of choice for localized muscle pain. Topical analgesics offer the potential to provide the same analgesic relief provided by oral analgesics but with minimal adverse systemic effects. The aim of this study is to present the preparation and characterization of topical analgesic gel named ＂Russian water＂. Gel is composed of Menthol, Benzocaine, Procaine HCl as topical analgesic agents indicated for temporary relief of pain. Obtained results showed prolonged analgesic effect compared with liquid ethanol solution composed of the same components.

关 键 词：Pain GEL Russian water antirheumatic analgesic. 

分 类 号：TQ461[化学工程—制药化工] S859.79[农业科学—临床兽医学]