基于对巯基苯硼酸的糖敏感水凝胶的制备  

Preparation of glucose-responsive hydrogels based 4-mercapto-phenylboronic acid

作　　者：王彦霞[1] 智爽 柴志华[1] 

机构地区：[1]华北科技学院,北京东燕郊101601

出　　处：《华北科技学院学报》2017年第1期91-94,共4页Journal of North China Institute of Science and Technology

基　　金：中央高校基本科研业务费(3142015080)

摘　　要：本文通过简单直接混合海藻酸钠、对巯基苯硼酸和Ca Cl2构建水凝胶。通过扫描电子显微镜观察到水凝胶具有明显的大孔多孔结构。溶胀实验证实随着对巯基苯硼酸浓度的增加,水凝胶的稳定性逐渐增强。此外,随着溶液中葡萄糖浓度的增加,凝胶降解速率逐渐加快。该多孔糖敏感水凝胶有望作为药物载体用于糖尿病的治疗。In phenylboronic this paper, the hydrogels were fabricated by simple mixing of sodium acid, and CaC12. The scanning electron microscope images of hydrogels alginate, 4 - mercapto - exhibited a highly macro- pronounced with the increase in the concentration of with spongelike structure were expected to serve as a glucose in solutions. The glucose- responsive hydrogels drug carrier for the treatment of diabetes.

关 键 词：海藻酸钠 对巯基苯硼酸 水凝胶 糖敏感性 

分 类 号：TQ427.26[化学工程]