头颈部肿瘤在自适应放疗中的研究进展  

Progress in Research of Adaptive Radiation Therapy for Head and Heck Cancer

作　　者：王志强[1] 李荣清[1] 张勇[1] 

机构地区：[1]昆明医科大学第一附属医院肿瘤放疗科,云南昆明650032

出　　处：《昆明医科大学学报》2016年第12期131-134,共4页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(81560462);云南省自然科学基金资助项目(2016FB150);云南省科技厅"惠民"基金资助项目(2014RA072)

摘　　要：放射治疗是头颈部肿瘤治疗中非常重要的治疗手段之一.其中调强放射治疗(intensity-modulated radiotherapy,IMRT)具有更好的适形性和均匀性,正逐步取代传统二维放射治疗成为头颈部肿瘤主流的放射治疗手段.但是调强放疗过程中,摆位误差,治疗方法和解剖结构的变化等,影响调强放射治疗的精准性,可能导致靶区欠量和(或)造成额外的并发症.自适应放射治疗是一种新型的放疗技术,它通过患者的先前的治疗图像、受照射剂量等反馈信息对原治疗计划重新优化和调整,能够修正调强放射治疗过程中的肿瘤靶区范围和提高疗效.在自适应放射治疗(adaptive radiotherapy,ART)技术的应用下,放疗技术会更加精准化、个体化.对ART技术在头颈部肿瘤中的研究现状作一综述.Radiotherapy is one of the most important treatment method for head and neck cancer. The inten- sity-modulated radiotherapy （IMRT） has better conformal property and uniformity. IMRT is gradually replacing conventional radiation therapy and has become the mainstream radical treatment for head and neck cancer. During IMRT, the patient treatment positioning, inter-treatment, and intra-treatment variation of organ position, size, and shape impact the accuracy of radiation dose delivery. This method may cause target less and （or） additional complications. Adaptive radiotherapy （ART） is a new radiotherapy technology. Based on the patient＇ s pre-treat- ment images and relative information such as dose deviation, ART can able to compensate the target coverage and clinical outcome. Under the help of ART technique, radiotherapy can be more accurate and more personalized. This paper reviews the research status of ART technology in head and neck cancerby retrospective studying the relat- ed literature at home and abroad.

关 键 词：自适应放疗 头颈部肿瘤 精准放疗 

分 类 号：R739.91[医药卫生—肿瘤]