Cancer Cell：新型药物组合或有望治疗恶性白血病  

Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for Cancer

作　　者：Nidal E. Muvarak  Khadiza Chowdhury  Limin Xia  Carine Robert  Eun Yong Choi  Yi Cai  Marina Bellani  Ying Zou  Zeba N. Singh  Vu H. Duong  Tyler Rutherford  Pratik Nagaria  S?ren M. Bentzen  Michael M. Seidman  Maria R. Baer  Rena G. Lapidus  Stephen B. Baylin  Feyruz V. Rassool 

机构地区：[1] Department of Radiation Oncology, University of Maryland, Baltimore, MD 21201, USA [2] Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA [3] The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA [4] Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA [5] Laboratory of Molecular Gerontology, National Institute on Aging, Baltimore, MD 21224, USA [6] University of Maryland Marlene and Stewart Greenebaum Cancer Center, Baltimore, MD 21201, USA [7] Stevenson University, Stevenson, MD 21153, USA [8] Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA [9] Veterans Affairs Medical Center, Baltimore, MD 21201, USA [10] Van Andel Research Institute, Grand Rapids, MI 49503

出　　处：《现代生物医学进展》2017年第11期I0003-I0003,共1页Progress in Modern Biomedicine

摘　　要：近日，刊登在国际杂志Cancer Cell上的一篇研究报告中，来自马里兰大学医学院等机构的研究人员开发了一种新型药物组合或有望帮助治疗急性髓性白血病（AML），在诊断为该疾病后，舭能在5年内使得几乎四分之三的患者死亡。目前在美国三个研究中研究研究人员正在招募研究者进行多中心的临床试验。

关 键 词：药物组合 CELL 白血病 治疗 恶性 研究人员 马里兰大学 临床试验 

分 类 号：S859.796[农业科学—临床兽医学]