抗HPV生物蛋白敷料治疗HPV高危感染合并宫颈CINⅠ的临床观察  

Anti-HPV biological protein dressing in the treatment of high risk HPV infection complicated with cervical CIN1

作　　者：霍艳芬 田旭青 霍墨杰 

机构地区：[1]衡水市第二人民医院妇产科,河北衡水053000

出　　处：《中国性科学》2017年第4期73-75,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨抗HPV生物蛋白敷料治疗HPV高危感染合并宫颈CINⅠ的疗效。方法:选取2012年2月至2015年11月期间在我院门诊就诊患者,选取146例HPV高危感染合并宫颈CINⅠ患者,随机分为研究组和对照组,研究组84例,采用抗HPV生物蛋白敷料阴道上药,每次1支,隔日1次,10次为1个疗程,连用3个疗程。对照组62例,未使用药物,仅做观察。结果:在第4个月复查宫颈脱落细胞学检查和HPV检测,研究组总有效率为80.95%,对照组总有效率为46.67%,两组比较,差异有统计学意义(P<0.05)。研究组宫颈脱落细胞学检查转阴率为80.77%,对照组转阴率为31.58%,两组比较,差异有统计学意义(P<0.05)。结论:抗HPV生物蛋白敷料治疗HPV高危感染合并宫颈CINⅠ可能有效,未发现不良反应。Objectives：To investigate the efficacy of anti HPV biological protein dressing in the treatment of high risk HPV infection and cervical CIN1. Methods：146 patients with high-risk HPV infection complicated with cervical CIN1 in out-patient department of our hospital from February 2013 to November 2015 were selected and randomly divided into study group and control group. The 84 patients in the study group received a vessel of anti HPV fibrin dressing vaginal irrigation every other day for 3 courses,10 times as a course of treatment. The 62 patients in the control group received no treatment. Results：In the 4thmonth review,the cure and effective rate of study group was 80. 95% and that of the control group was 46. 67%. Difference in the HPV clearance rate between the two groups was statistically significant（P 0. 05）. The cervical exfoliated cytology negative rate of study group and control group was 80. 77% and 31. 58% respectively,with statistically significant difference（P 0. 05）.Conclusion：Anti HPV biological protein dressing is effective in the treatment of high-risk HPV infection complicated with cervical CIN1,without noticed adverse reactions.

关 键 词：抗HPV生物蛋白敷料 HPV高危感染合并宫颈CINⅠ HPV检测 宫颈脱落细胞学检查 

分 类 号：R711.74[医药卫生—妇产科学]