儿童屈光状态对干眼的影响  

Effect of refractive state on dry eye in children

作　　者：郭元懿[1] 李若溪[1] 

机构地区：[1]沈阳市第四人民医院眼科,沈阳110031

出　　处：《中国实用眼科杂志》2017年第3期295-298,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的 了解儿童屈光状态对儿童干眼的影响，探讨儿童干眼的影响因素及临床特点。方法 采取临床病例对照研究。选取2014年10月至2016年3月在沈阳市第四人民医院眼科就诊的450例轻度屈光不正的儿童（轻度近视、轻度远视、轻度散光各150例）和150例正视眼儿童。收集各组病例的视力、屈光度、主要临床症状、Schirmer Test（泪液分泌试验）、BUT（泪膜破裂时间）、FL（角膜荧光素染色）等临床资料。结果 儿童干眼症的主要临床症状表现为频繁瞬目，轻度屈光不正儿童干眼症发病率高于正视眼儿童干眼症的发病率。各组干眼症发病率存在显著差异（χ2=30.475，P=0.000）。其中轻度散光组中发病率最高，其次是轻度远视组，两者之间差异有统计学意义（P〈0.05）。轻度散光组和轻度远视组BUT时间缩短。其中散光组最明显，其次是轻度远视组，两者之间差异有统计学意义（P〈0.05）。而Schirmer test和FL各组之间差异无统计学意义（P〉0.05）。结论 儿童的轻度屈光不正和干眼症密切相关。主要临床表现是频繁瞬目，泪膜稳定性下降，BUT缩短。其中散光及远视对儿童干眼症的影响较为明显。Objective To investigate the effect of refractive state on dry eye in children, and to explore the influencing factors and clinical characteristics of dry eye in children.Methods Take the clinical case-control study. A total of 450 cases of mild ametropic children （150 cases of mild myopia; 150 cases of mild hyperopia; mild astigmatism in 150 cases） and 150 cases of emmetropia were selected from October 2014 to March 2016 in Shenyang Fourth People＇s Hospital. The vision, diopter, main clinical symptoms, Schirmer Test, BUT （break-up time）, FL （corneal fluorescein staining） and other clinical data were collected from the patients in each group.Results The main clinical symptoms of dry eye in children were frequent blinking. The incidence of dry eye in mild ametropic children xerophthalmia was higher than that of emmetropic children. The refractive group incidence of dry eye syndrome had significant differences. （χ2=30.475, P=0.000）. The mild astigmatism group had the highest incidence, followed by mild hyperopic group. There were significant differences P 〈0.05 between the two exists. BUT time in mild astigmatism group and mild hyperopia group was shortened. The astigmatism group was the most obvious, followed by mild hyperopic group; there existed significant differences （P 〈0.05） between them. However, there were no significant difference （P 〉0.05） on Schirmer test and FL between two groups.Conclusions Children of mild refractive error and dry eye syndrome is closely related. Main and clinical expression is frequent eye blink, tear film stability decrease, BUT shorten. The influence of astigmatism and hyperopia on dry eye in children is obvious.

关 键 词：儿童 屈光不正 干眼 

分 类 号：R591.412[医药卫生—内科学]