棒状光源盐酸5-氨基酮戊酸光动力治疗肛管内尖锐湿疣  

Topical 5-aminolevulinic acid photodynamic therapy with stick light source in the treatment of intra anal-rectal warts

作　　者：赵伟[1,2,3] 单晓峰[2,3] 王长亮[2,3] 刘鑫洲[2,3] 李珍[2,3] 李中伟[2,3] 郑荣涛[2,3] 侯建玲[2,3] 田洪青[1,2,3] 

机构地区：[1]济南大学山东省医学科学院医学与生命科学学院,济南250000 [2]山东省皮肤病性病防治研究所,济南250022 [3]山东省皮肤病医院,济南250022

出　　处：《中国麻风皮肤病杂志》2017年第4期205-208,共4页China Journal of Leprosy and Skin Diseases

基　　金：山东省科技发展计划(编号:2014GSF118104)

摘　　要：目的:评价棒状光源盐酸5-氨基酮戊酸光动力疗法治疗肛管内尖锐湿疣的临床疗效。方法:棒状光源盐酸5-氨基酮戊酸治疗肛管内尖锐湿疣男性患者46例,每周1次,共4次。结果:35例(76.1%)患者疣体完全清除,无感染、溃疡、瘢痕、痔疮病例。随访12周复发5例,复发率为14.3%。疼痛程度可视模拟评分(VAS)为(6.96±1.41)分。结论:棒状光源盐酸5-氨基酮戊酸治疗肛管内尖锐湿疣疗效好,中度疼痛,复发率低,不良反应少。Objective：To assess the efficacy of hydrochloric 5-aminolevulinic acid photodynamic therapy （ALA-PDT） with stick light source in the treatment of intra anal-rectal warts.Methods：Forty-six male patients with intra anal-rectal warts were treated with ALA-PDT （stick light source）, once a week for 4 weeks.Results：The warts body was completely removed in 35 cases （76.1%）.There was no infection, ulcer, scar and hemorrhoids.Five patients recurred after 12 weeks of follow-up with a recurrence rate of 14.3%.The score of pain visual analogue scale （VAS） was 6.96±1.41 points.Conclusion：ALA-PDT with stick light source in the treatment of intra anal-rectal warts had good effect, moderate pain low recurrence rate and less adverse reactions.

关 键 词：盐酸5-氨基酮戊酸光动力 棒状光源 肛管内 尖锐湿疣 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]