累积高敏C反应蛋白水平与踝臂血压指数的相关性  

Correlation between cumulative high sensitivity C-reactive protein and ankle brachial index

作　　者：崔凯[1,2] 于俊杏 赵权辉 李蔚[1,2] 张芮英 宋路[1,2] 赵华灵[1,2] 李春慧[1,2] 陈朔华[2] 吴寿岭[2] 

机构地区：[1]华北理工大学研究生院,河北唐山063000 [2]开滦总医院心内科

出　　处：《中华高血压杂志》2017年第3期252-257,共6页Chinese Journal of Hypertension

摘　　要：目的探讨累积高敏C反应蛋白(cumCRP)与踝臂血压指数(ABI)的关系。方法本研究对完成ABI检测的观察对象11 933人进行分析,年龄(51.7±14.3)岁,其中男性7260人,占60.8%。依据cumCRP四分位将总人群分为4组,观察cumCRP对ABI的影响。结果随着cumCRP的增加,ABI<0.9的检出率逐渐增加(分别为2.9%、2.8%、3.1%、4.5%;P<0.05)。多因素logistic回归分析校正年龄、性别等混杂因素后,与第1四分位组相比,第2、3、4四分位组ABI<0.9的OR值(95%CI)分别为0.87(0.57~1.34)、0.93(0.60~1.42)和1.66(1.03~2.35)。结论 cumCRP是ABI<0.9的危险因素。Objective To investigate the association between cumulative high sensitivity C-reactive protein （cumCRP} and ankle brachial index（ABI）. Methods A total of 11 933 individuals with mean age of （51.74-14.3） years old were enrolled, in which 7260 （60.8%） were male. According to cumCRP quartile, the individuals were divided into four groups. The association between cumCRP and ABI was analyzed. Results The incidence of ABI 〈0.9 increased with the cumCRP increase （the incidence in four groups with cumCRP from low to high was 2.90%, 2.8%, 3.1%and 4.5 %, respectively）. Multivariate logistic regression analysis showed that compared with the quartile 1 group, the OR （95% CI） for ABI 〈0.9 in quartile 2, quartile 3 and quartile 4 group were 0.87 （0.57- 1.34）, 0.93 （0.60-1.42 ） and 1.66 （1.03-2.35）, respectively. Conclusion cumCRP is correlated significantly with ABI〈0.9.

关 键 词：累积C反应蛋白 踝臂血压指数 相关性 

分 类 号：R541.4[医药卫生—心血管疾病]