局部冷刺激结合中低强度运动对学龄前儿童免疫功能的影响  

Effect of partial cold stimulation combined low-middle intensity exercise on immune function in preschool children

作　　者：许国钧 陈兆 

机构地区：[1]舟山市普陀区中医院儿科,316100

出　　处：《浙江医学》2017年第8期638-640,共3页Zhejiang Medical Journal

基　　金：国家科技支撑计划重大课题项目(2009BAK62B02-015)

摘　　要：目的通过检测学龄前儿童局部冷刺激结合中低强度运动干预前后免疫球蛋白、T淋巴细胞的变化,探讨其对学龄前儿童免疫功能的影响。方法选取幼儿园学龄前儿童82人,按随机数字表法将学龄前儿童分为实验组(42人)和对照组(40人)。两组儿童均参与幼儿园组织的正常体育运动,在此基础上实验组儿童采取局部冷刺激结合中低强度运动的干预方案。干预前后分别采集两组儿童静脉血标本行血清免疫球蛋白IgA、IgG、IgM水平和CD3^+、CD4^+、CD8^+T淋巴细胞比率检测并进行比较。结果实验组儿童干预后免疫球蛋白IgA、IgG、IgM水平和CD3^+、CD4^+、CD8^+T淋巴细胞比率均高于干预前(均P<0.05)。对照组儿童干预后免疫球蛋白IgM水平和CD3^+、CD8^+T淋巴细胞比率均高于干预前(均P<0.05),而免疫球蛋白IgA、IgG水平和CD4^+T淋巴细胞比率与干预前比较均并无统计学差异(均P>0.05)。结论局部冷刺激结合中低强度运动可改善学龄前儿童的免疫功能。Objective To investigate the effect of partial cold stimulation combined low-middle intensity exercise on immune function in preschool children. Methods Eighty two preschool children in kindergarten were randomly divided into study group（42persons） and control group（40 persons）. Children in both groups participated in normal exercise,those in study group received additional intervention of partial cold stimulation combined low-middle intensity exercise. The serum levels of IgA,IgG,IgM and CD3＋,CD4＋,CD8＋T lymphocytes were measured and compared between the two groups before and after the intervention. Results The levels of IgA,IgG,IgM and CD3＋,CD4＋,CD8＋T lymphocytes in study group were higher than those before the intervention（P〈0.05）. The levels of IgM and CD3＋ and CD8＋T lymphocytes in control group were significantly higher than those before intervention（P〈0.05）,while there were no significant differences in the levels of IgA,IgG and CD4＋T lymphocytes before and after intervention（P〈0.05）. Conclusion Partial cold stimulation combined low-middle intensity exercise can improve the immune function of preschool children.

关 键 词：冷刺激 学龄前儿童 免疫功能 运动 

分 类 号：R725[医药卫生—儿科]