呼吸道微生态在大气污染中的改变与调节的研究进展  

Research advances on the change and regulation of airway micro-ecology in air pollution

作　　者：张瑜[1] 肖纯凌[1] 

机构地区：[1]沈阳医学院环境污染与健康重点实验室,辽宁沈阳110034

出　　处：《中国当代医药》2017年第12期12-15,共4页China Modern Medicine

基　　金：辽宁省沈阳市科学技术项目(F14-181-1-00)

摘　　要：大气污染物是由自然和人类活动所产生的各种固态和液态颗粒状物质的总称,易于吸附空气中悬浮的金属离子、无机成分、有机成分、生物物质等。当其进入呼吸道后,吸附在黏膜上,引起呼吸道微生态的异常改变。甲型链球菌等口咽部正常菌群减少或外籍菌入侵,能够打破微生态平衡,引起呼吸道感染。应积极探究呼吸道菌群之间的相互拮抗作用,选取有益菌制成微生态制剂,倡导益生菌治疗。本文就大气污染物的主要组成及其理化性质、大气污染与人群呼吸道疾病的流行病学调查、机体呼吸道微生态改变的预测、大气污染对呼吸道疾病的影响、大气污染对呼吸系统的影响趋势、呼吸道菌群益生菌的探索进行综述。Air pollutants are varieties of solid and liquid particulate matter generated by natural and human activities. The pollutants are easy to absorb the air suspended metal ions,inorganic components,organic ingredients,biological substances, etc..When entering into respiratory tract and adsorbing on the mucous membrane,it causes abnormal changes in the respiratory tract micro-eeology.A reduction in the normal flora of the mouth,such as Streptococcus type A,or the in- vasion of foreign bacteria,can break the micro ecological balance,causing respiratory infections.The mutual antagonism between the respiratory tract flora should he beneficial to actively explore,and Probioties should he selected, Probiotics treatment should he initiated.In this paper,the main atmospheric pollutant composition and physicochemieal properties, atmospheric pollution and human respiratory disease epidemiology,the respiratory tract microecology change predictiont, the influence of air pollution on the respiratory system,the influence trend of air pollution on respiratory system and the exploration of respiratory tract flora probiotics were reviewed.

关 键 词：大气颗粒物 呼吸道微生态 甲型链球菌 呼吸道感染 益生菌 

分 类 号：R122.7[医药卫生—环境卫生学]