常规治疗联合肺表面活性物质治疗早产儿呼吸窘迫综合征的效果  

Effect of conventional treatment combined with lung surface active substance in the treatment of premature infant respiratory distress syndrome

作　　者：陈少丽[1] 乔萍[1] 王伟名[1] 黎金文 

机构地区：[1]广东省肇庆市第一人民医院新生儿科,广东肇庆526000

出　　处：《中国当代医药》2017年第12期84-86,共3页China Modern Medicine

摘　　要：目的探讨常规治疗联合肺表面活性物质治疗早产儿呼吸窘迫综合征的效果。方法选取2008年2月~2016年2月我院收治的早产儿呼吸窘迫综合征患儿100例,将其随机分为观察组和对照组,每组50例。对照组给予常规治疗,观察组在对照组基础上给予肺表面活性物质治疗。比较两组患儿治疗前后的血气与氧合功能指标以及治疗后的机械通气时间、氧疗时间、住院时间和临床效果。结果观察组治疗后的血气与氧合功能指标均明显优于对照组(P<0.05);观察组治疗后的机械通气、氧疗和住院时间均短于对照组(P<0.05);观察组的治疗效果明显优于对照组(P<0.05)。结论肺表面活性物质治疗早产儿呼吸窘迫综合征,缩短了住院时间、氧疗时间和机械通气时间,并明显改善了血气与氧合功能,治疗后效果显著,值得在临床上进一步推广使用。Objective To study the conventional treatment combined with lung surface active substance in the treatment of premature infant respiratory distress syndrome.Methods From February 2008 to February 2016,100 cases of children with premature respiratory distress syndrome were selected and randomly divided into observation group and the control group,50 cases in each group.Control group was given conventional treatment,and the observation group was given the lung surface active substance on the basis of the control group.The blood gas and oxygenation function index before and after treatment,and time of mechanical ventilation,oxygen therapy after treatment,length of hospital stay and clinical effect of children were compared between the two groups.Results After treatment,blood gas and oxygenation function index of the observation group were better than those of the control group（P〈O.OS）;the time of mechanical ventilation,oxygen therapy after treatment,length of hospital stay of the observation group were shorter than those of the control group （P〈0.05）;the treatment effect of observation group was obviously better than that of control group （P〈0.05）.Conclusion In treatment of premature infant respiratory distress syndrome,the lung surface active substance has shorten the length of hospital stay,time of oxygen therapy and mechanical ventilation,and has obviously improved the lood gas and oxygenation function,treatment effect is remarkable,it is worthy of further application in clinic.

关 键 词：早产儿呼吸窘迫综合征 肺表面活性物质 氧疗时间 治疗效果 

分 类 号：R722.1[医药卫生—儿科]