枸橼酸钠注射液溶血性试验  

作　　者：孟凡佳[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《黑龙江科技信息》2017年第1期27-27,共1页Heilongjiang Science and Technology Information

摘　　要：目的:观察枸橼酸钠注射液与日本大耳白兔红细胞混悬液温育后是否产生溶血现象和红细胞凝聚现象,对其溶血性做出评价,为该药物的临床安全应用提供参考依据。方法:采用体外试管法,以临床使用浓度(供试品原液)进行试验,观察该注射液对家兔红细胞的溶血作用。结果:枸橼酸钠注射液组对家兔红细胞未出现溶血和凝聚现象。结论:在本实验条件下,枸橼酸钠注射液未出现溶血和红细胞凝聚现象,符合注射用药物安全性检查的要求。ObjectionTo observe the hemolysis and erythrocyte aggregation phenomena of sodium citrate injection, to evaluate the hemolytic, provide the reference for the clinical application in the safety of the drug.MethodBy test tube method in vitroused clinical concentration （for sample solution）to testing and observation of the injection on rabbit red＂ blood cell hemolysis.Resuh The citrate injection group had no hemolysis and coagulation phenomenon. ConclusionUnder the condition of this experiment, the citrate injection did not appear hemolysis and erythroeyte aggregation, conform to injection drug safety inspection requirements.

关 键 词：枸橼酸钠注射液 供试品原液 溶血性 

分 类 号：S858.291[农业科学—临床兽医学]