舒肝方治疗原发性轻中度干燥综合征105例临床研究  

Clinical Study on the Therapeutic Effect of the Using Shugan Formula to Treat 105 Cases of Mild to Moderate Primary Sjogren's Syndrome

作　　者：陈文婷[1] 单丽娟[1] 王华[2] 袁征[3] 陈润 顾军花[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032 [2]上海市中西医结合医院,上海200082 [3]上海市第八人民医院,上海200235 [4]上海嘉定区南翔镇社区卫生服务中心,上海200082

出　　处：《山东中医杂志》2017年第4期304-306,共3页Shandong Journal of Traditional Chinese Medicine

基　　金：上海市卫计委三年行动计划专项课题(编号:ZY3-J SFC-2-2004);上海市科委课题(编号:12401904000)

摘　　要：目的:观察舒肝方治疗轻中活动度干燥综合征(SS)的疗效。方法:确诊的105例SS患者,均服用自拟舒肝方加减,治疗3个月,观察治疗前后的临床症状及实验室指标变化。结果:经过3个月的治疗,患者口干、眼干、皮肤干临床症状积分较治疗前均明显减少(P<0.01);泪液试验、含糖试验、类风湿因子(RF)、免疫球蛋白G(Ig G)较治疗前均明显改善(P<0.01);红细胞沉降率(ESR)、C反应蛋白(CRP)较治疗前差异无统计学意义(P>0.05)。结论:舒肝方可以明显控制及改善轻中度原发性干燥综合征的临床症状和实验室指标。Objective：To evaluate curative effect of Shugan formula to treat mild to moderate primary Sjo- gren＇s syndrome. Methods：There are 105 patients with Sjogren＇s syndrome,and they were treated with the Shugan formula for 3 months,and the changes of symptoms and laboratory indexes were examined to evalu- ate the effect. Results：After treated for 3 months,dryness of mouth,eyes and skin was relieved with the score reduced compared with before treatment（P〈0.01）,and immunoglobulin G,rheumatoid factors,tear test and sugar test were changed significantly（P〈0.01）. However,there was no significant difference on the ery throcyte sedimentation rate and C reactive protein in Sjogren＇s syndrome between before treatment and after treatment（P〉0.05）. Conclusion：Shugan formula could effectively improve the clinical symptoms and laborato- ry indexes of mild to moderate primary Sjogren＇s syndrome.

关 键 词：干燥综合征 中医治疗 舒肝方 

分 类 号：R259.932[医药卫生—中西医结合]