药疹189例临床分析  

Clinical Analysis of 189 Cases of Drug Eruption

作　　者：单偶奇 安莉[2] 赵文伟[2] 

机构地区：[1]哈尔滨工程大学医院,黑龙江哈尔滨150001 [2]西安交通大学第二附属医院,陕西西安710004

出　　处：《中国皮肤性病学杂志》2017年第5期511-513,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的了解药疹发生的特点和规律,为促进临床合理用药提供参考。方法收集2012-2015年在西安航天总医院住院的189例药疹患者的病历资料,对患者性别、年龄、药品种类、药疹分型、治疗等方面进行统计分析。结果 189例药疹患者中,男83例,女106例,其中60~80岁的患者发生率最高,为29.63%。抗生素药物导致的药疹例数居首位,其次为中成药、非甾体抗炎药物、生物制剂等。重症药疹患者的比例占6.87%。结论应该重视抗生素药物的正确使用,尤其应该注意老年患者的药物使用,注意防范重症药疹的发生;早期足量系统使用糖皮质激素是治疗重症药疹的关键。Objective To understand the characteristic and regularity of drug eruption, and to provide rationale for proper use of drugs in clinics.Methods Gender and age, types of drugs, types of drug eruption and treatment were analyzed in 189 patients with drug eruption hospitalized at Xi＇an aerospace general hospital from 2012 to 2015.ResultsOne hundred and eighty-nine patients included 83 males and 106 females.The highest incidence（29.63%）occurred in the patients aged 60 to 80 years.Antibiotics were the major cause of drug eruption, followed by Chinese proprietary medicines, non-steroidal anti-inflammatory drugs, biological agents, etc.The incidence of severe drug eruption was 6.87%.Conclusion It is necessary to standardize the use of antibiotics, especially for the elderly.Special attention should be paid to the prevention of severe drug eruptions.In treating severe drug eruptions, it is crucial to early and systemically give sufficient corticosteroids.

关 键 词：药疹 药物 不良反应 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]