MSM人群HIV感染者梅毒RPR试验假阳性分析  

Analysis of RPR False-positive in MSM with HIV Infection

作　　者：李娟[1] 张明[1] 夏炜[1] 闫俊玲[1] 高艳青[1] 

机构地区：[1]首都医科大学附属北京佑安医院,北京100069

出　　处：《中国皮肤性病学杂志》2017年第5期529-530,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的了解男男同性恋者(MSM)中人类免疫缺陷病毒(HIV)感染者梅毒快速血浆反应素环状卡片试验(RPR)生物学假阳性反应(BFP)情况。方法对我院MSM人群筛查队列进行RPR试验、梅毒螺旋体明胶凝集试验(TPPA)试验和HIV抗体初筛,比较梅毒RPR生物学假阳性(RPR-BFP)发生情况。结果共10 000例MSM,HIV抗体阳性者中,RPR-BFP 0.15%(3/1 989);HIV抗体阴性者中,RPR-BFP0.27%(22/8 011)。该两组人群RPR试验假阳性率差异无统计学意义(P>0.05)。结论 HIV感染没有增加梅毒RPR生物学假阳性反应。Objective To determine whether HIV infection affects biological false positive（BFP）for Rapid plasma regain（RPR）in populations of “men sex with men（MSM）”.Methods Screening of RPR、TPPA and HIV antibody was performed in a cohort of MSM.The incidence of BFP for RPR（RPR-BFP）was compared in HIV＋ vs.HIV-.Result A total of 10,000 MSM subjects were tested.The rates of RPR-BFP were no significant differences in HIV＋ vs.HIV-groups [0.15%（3/1 989）vs.0.27%（22/8 011）,p.0.05].Conclusion HIV infection does not affect the rate of RPR-BFP.

关 键 词：人类免疫缺陷病毒 梅毒 RPR生物学假阳性 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]