青蒿素抗疟研究的不断追求:快速消灭疟疾——纪念执行“523”任务50周年  

Persistent Pursuit in Research of Artemisinin:Fast Elimination of Malaria Commemoration for the 50th Anniversary of Project 523

作　　者：李国桥[1] 郭兴伯[1] 符林春[1] LI Guo-Qiao GUO Xing-Bo FU Lin-Chun(Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, China)

机构地区：[1]广州中医药大学,广东广州510405

出　　处：《广州中医药大学学报》2017年第3期303-307,共5页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：在国家"523"(防治疟疾新药项目代号)任务实施50周年之际,对广州中医药大学青蒿素抗疟研究科研团队采用青蒿素复方防治疟疾的历程与所取得的进展进行评述。广州中医药大学作为"523"项目研究小组之一,其青蒿素抗疟研究科研团队相继主持了采用青蒿素及其衍生物不同剂型、剂量、疗程治疗疟疾的临床研究(1974~1989)、青蒿素复方(Artekin及Artequick)治疗疟疾的临床研究(1984~2006),并于近10年中在东南亚地区及非洲全力推行快速消灭传染源清除疟疾(Fast Elimination of Malaria by Source Eradication,FEMSE)的抗疟项目。青蒿素抗疟研究科研团队所做的探索与获得的成就为青蒿素类药物走向世界做出了重要贡献,并为全球快速消灭疟疾创建了一种简单、易行、省钱的新方法。At the 50th Anniversary of Project 523, we reviewed the course and progress made by the Artemisinin Anti-malaria Research Group of Guangzhou University of Chinese Medicine in the application of artemisinin for treating malaria. As one of the groups participating in the mission of Project 523, Artemisinin Anti-malaria Research Group of Guangzhou University of Chinese Medicine was in charge of the clinical trials in treating malaria with artemisinin andits derivatives of various preparation forms , dosages and treatment courses（years 1974-1989）, developed the artemisinin-based combinations （ACTs） Artekin and Artequick for malaria treatment and performed their clinical trials（years 1984 - 2006）. For the recent 10 years, the group has been devoted in the implementation of anti-malaria programme FEMSE （Fast Elimination of Malaria by Source Eradication） in south-east Asia and Africa. The scientific explorations and achievements of this research group have made great contribution in bringing artemisinins to the world and creating a simple, practical and cost-effective new method for rapid global malaria elimination.

关 键 词：青蒿素 青蒿素复方 快速灭源灭疟项目(FEMSE) 疟疾 广州中医药大学 

分 类 号：R254.5[医药卫生—中医内科学]