磁共振扩散张量成像定量分析正常巴马小型猪腰椎神经根各向异性分数特征  

Magnetic Resonance Diffusion Tensor Imaging Quantitative Analysis of Fractional Anisotropy Characteristics of Normal Bama Miniature Pig Lumbar Nerve Roots

作　　者：植彪 彭涛[1] 牛翔科 陈云涛[1] 肖建明[1] Zhi Biao Peng Tao Niu Xiangke et al(Department of Radiology,Affiliated Hospital of Chengdu University, Chengdu , Sichuan 610081, China)

机构地区：[1]成都大学附属医院放射科,四川成都610081

出　　处：《四川医学》2017年第4期381-384,共4页Sichuan Medical Journal

基　　金：四川省医学科研青年创新课题计划(编号:Q14004)

摘　　要：目的探索正常巴马小型猪腰椎神经根磁共振弥散张量成像(diffusion tensor imaging,DTI)的各向异性分数(fractional anisotropy,FA)特征。方法选择10只健康巴马小型猪,采用1.5T磁共振DTI扫描,测定腰1~腰5双侧神经根FA值,并比较同一节段双侧神经根及不同节段间上下神经根FA值的差异。结果腰1~5神经根的FA值从上到下逐渐增加,双侧神经根FA值的均值分别为(0.215±0.051)mm^2/s、(0.235±0.060)mm^2/s、(0.306±0.073)mm^2/s、(0.402±0.094)mm^2/s、(0.472±0.090)mm^2/s。同一节段双侧神经根间FA值的差异无统计学意义(P>0.05)。腰1与腰2、腰4与腰5神经根FA值的差异无统计学意义(P>0.05),腰1、2分别与腰3、4、5神经根相比、腰3与腰4、5神经根相比上下各神经根各向异性分数FA值差异有统计学意义(P<0.05)。结论 DTI的FA值测量可以对正常巴马小型猪腰椎神经根进行定量分析,其测量结果可为定量评价非压迫性神经根炎微创治疗提供实验依据。Objective To explore the fractional anisotropy（ FA） characteristics of the normal Bama miniature pig lumbar nerve roots in magnetic resonance diffusion tensor imaging（ DTI）. Methods 10 healthy Bama miniature pigs was selected and scanned using 1. 5T DTI to determine the FA values of lumbar 1 to 5 bilateral nerve roots. FA values of bilateral nerve roots at the same segment and FA values of nerve roots at different segments were compared. Results FA values of Lumbar1 to 5 nerve roots increased gradually from top to bottom and the mean FA values of bilateral nerve roots were（ 0. 215 ± 0. 051） mm^2/s,（ 0. 235 ±0. 060） mm^2/s,（ 0. 306±0. 073） mm^2/s,（ 0. 402±0. 094） mm^2/s,（ 0. 472±0. 090） mm^2/s. Differences of FA values between bilateral nerve roots at the same segment was not statistically significant（ P〉0. 05）. The differences of FA values between Lumbar 1 and Lumbar 2 as well as Lumbar 4 and Lumbar 5 nerve roots were not statistically significant（ P〉0. 05）. Comparing Lumbar 1 and 2nerve roots with Lumbar 3,4 and 5 nerve roots,Lumbar 3,4 and 5 nerve roots had statistically significant difference with their upper and lower nerve roots on FA values（ P〈0. 05）. Conclusion FA values determination by DTI can quantitatively analyze lumbar nerve rootsof normal Bama miniature pigs and the measurement results can provide experimental basis for the quantitative evaluation of minimally invasive therapy for non-compressive nerve root inflammation.

关 键 词：磁共振成像 扩散张量成像 神经根 各向异性分数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681.5[医药卫生—诊断学]