中西医结合治疗下肢动脉硬化闭塞症疗效观察  

Clinical Observation on 60 Cases of Arteriosclerosis Obliterans of Lower Extremities Treated by Combination of TCM and Western Medicine

作　　者：李晓波[1] 郝占峰[1] 雷小明[1] 

机构地区：[1]河北省石家庄长城中西医结合医院周围血管科,河北石家庄050035

出　　处：《实用中医药杂志》2017年第5期520-521,共2页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察复脉饮、纤溶酶、前列地尔治疗下肢动脉硬化闭塞症的临床疗效。方法:120例随机分为治疗组与对照组各60例,治疗组给予复脉饮、纤溶酶、前列地尔治疗,对照组给予纤溶酶、前列地尔加安慰剂治疗,治疗1个月观察两组中医症候积分、踝肱指数、行走距离变化。结果:总有效率治疗组93.3%、对照组86.7%,两组比较差异有统计学意义(P<0.05);两组治疗后中医症候积分、踝肱指数、行走距离均较治疗前有明显改善(P<0.05),而观察组各指标改善优于对照组(P<0.05)。结论:复脉饮、纤溶酶、前列地尔治疗下肢动脉硬化闭塞症具有较好的临床疗效。Objective： To observe the therapeutic effect of self-made Fumai Decoction combined with plasmin and alprostadil in the treatment of lower extremities arteriosclerosis obliterans. Method： 120 cases were randomly divided into treatment group and control group, with 60 cases in each group. The treatment group were treated with self-made Fumai Decoction combined with plasmin and alprostadil while the control group were treated with plasmin, alprostadil and placebo. After 1 month＇ s treatment, the improvement of TCM syndrome integral, ankle brachial index and walking distance of the two groups was observed. Result： The total effective rate was 93.3% in treatment group while that of the control group was 86.7% （ P〈0.05 ） . There was significant difference between the two groups （P〈0.05） . TCM syndrome integral, ankle brachial index and walking distance of both groups after the treatment improved significantly compared with that before treatment （ P〈0.05 ） . After the treatment, the improvement of each index of the treatment group was superior to that of the control group （P〈0.05） .Conclusion： Self-designed Fumai decoction combined with plasmin and alprostadil has good clinical curative effect in the treatment of lower extremities arteriosclerosis obliterans.

关 键 词：下肢动脉硬化闭塞症 中西医结合 对照治疗观察 

分 类 号：R543.5[医药卫生—心血管疾病]