1例骨折术后并发急性呼吸窘迫综合征患者的药物治疗策略分析  

Analysis of Drug Treatment Strategy for One Case of ARDS after Fracture Operation

作　　者：杜丽芬[1] 吕操[1] 宋红萍[1] 胡建武[2] 

机构地区：[1]华中科技大学同济医学院附属普爱医院药学部,武汉430033 [2]华中科技大学同济医学院附属普爱医院呼吸内科,武汉430033

出　　处：《中国药师》2017年第5期877-880,共4页China Pharmacist

基　　金：武汉市卫生计生科研基金资助项目(编号:WX16B11;WZ16C20)

摘　　要：目的:探讨临床药师介入1例骨折术后并发急性呼吸窘迫综合征(ARDS)患者个体化治疗的切入点和监护要点。方法:临床药师充分评估患者病情后,查阅大量文献,对患者经验治疗中抗感染治疗的力度、具有争议的糖皮质激素使用与否,以及氨溴索的合理使用等方面提供建议,选定主观和客观指标,对治疗过程中药物的疗效和主要不良反应进行监护。结果:临床药师在糖皮质激素治疗的利弊、给药剂量、如何减量,以及抗菌药物给药剂量、氨溴索使用剂量和疗程等方面与医生达成共识,最终使该患者获得最大化的治疗收益。结论:临床药师可以摸索对特定病种的治疗和监护,找到介入临床医生和患者中的切入点,在临床上发挥一定作用,并逐渐积累治疗经验。Objective： To explore the entry points and monitoring pointz of individualized treatment for fracture surgery patients with ARDS. Methods： Clinical pharmacists comprehensively assessed the patient＇s conditions and looked up lots of literatures. Some suggestions on the anti-infection treatment efforts, glucocortieoid use dispute and rational use of ambroxol were offered. The efficacy and adverse reactions of drugs in the treatment process were monitored using some subjective and objective indicators. Results： The consensus about the pros and cons, dosages, as well as the possible dosage decrease of glucocorticoid therapy, the dosages of antimicrobial agents, and the dosages and treatment course of ambroxol was achieved between clinical pharmacists and doctors. As a result, the maximum benefits were obtained for the patient. Conclusion： Clinical pharmacists can explore the treatment and monitoring for specific diseases and find out intervention entry points of clinicians and patients to play a certain role in clinics, and accumulate treatment experience gradually.

关 键 词：急性呼吸窘迫综合征 糖皮质激素 替考拉宁 氨溴索 药物治疗 

分 类 号：R97[医药卫生—药品]