Role of fNIRS technology in observing the effect of needling Hegu(LI 4) on the functions of prefrontal cortex in healthy volunteers  

应用fNIRS技术观察针刺合谷穴对健康人前额叶皮层功能影响的研究（英文）

作　　者：韩雅迪 袁博 张彦峰 王喜凤 浪万英 严兴科 韩丑萍(译) 

机构地区：[1]School of Acupuncture and Tuina, Gansu University of Chinese Medicine, Lanzhou 730000, China [2]不详

出　　处：《Journal of Acupuncture and Tuina Science》2017年第2期94-98,共5页针灸推拿医学（英文版）

基　　金：supported by Project of National Natural Science Foundation of China No.81460744;Project of Natural Science Foundation of Gansu Province No.1308RJZA150~~

摘　　要：Objective： To observe the effect of needling Hegu （LI 4） on functions of the prefrontal cortex using the functional near infrared spectroscopy （fNIRS）. Methods： A total of 12 healthy volunteers were randomly assigned to an acupuncture group （n=6） and a control group （n=6）. The control group received no intervention. The acupuncture group received needling Hegu （LI 4） on the right side. The real-time concentration changes of oxygenated hemoglobin （HbO2）, deoxygenated hemoglobin （d-Hb） and total hemoglobin （t-Hb） in the prefrontal cortex were recorded using the fNIRS, allowing for effect analysis of needling Hegu （LI 4） on the functions of the prefrontal cortex. Results： Compared with the control group, the HbO2 and t-Hb concentrations were increased in the acupuncture group and there were between-group statistical significances （bothP〈0.05）. There was no between-group statistical significance in d-Hb concentration （P〉0.05）. Conclusion： Needling Hegu （LI 4） can extensively activate the prefrontal cortex and therefore has significant effect on the functions of the brain＆#39;s prefrontal cortex.目的:利用功能近红外光谱成像(fNIRS)技术观察针刺合谷穴对健康人前额叶皮层功能的影响。方法:将12名健康受试者根据随机数字表随机分为对照组和针刺组,每组6例。对照组不予任何干预,针刺组予以针刺右侧合谷穴。利用近红外脑功能成像仪实时记录前额叶皮层区含氧血红蛋白(HbO_2)、脱氧血红蛋白(d-Hb)和总血红蛋白(t-Hb)的浓度变化,分析针刺合谷穴对前额叶皮层功能的影响。结果:与对照组比较,针刺组HbO_2和t-Hb浓度增高,组间差异均有统计学意义(均P<0.05);而d-Hb浓度组间差异无统计学意义(P>0.05)。结论:针刺合谷穴能引起前额叶皮层的广泛激活,对前额叶皮层脑功能有明显的影响。

关 键 词：Acupuncture Therapy Point Prefrontal Cortex HEMOGLOBIN Healthy Volunteers 

分 类 号：R2-03[医药卫生—中医学]