2014年-2015年浙江嘉善成人病毒性腹泻病原分布与流行特征分析  

Analysis of pathogen distribution and epidemic characteristics of viral diarrhea in adults during 2014-2015 in Jiashan,Zhejiang

作　　者：陈云[1] 朱建民[1] 袁永娟[1] 凌勤芳[1] 陈寅[2] 

机构地区：[1]嘉善县疾病预防控制中心,浙江嘉善314100 [2]浙江省疾病预防控制中心,浙江杭州310051

出　　处：《中国卫生检验杂志》2017年第8期1161-1163,共3页Chinese Journal of Health Laboratory Technology

基　　金：浙江嘉善科技局计划项目(2014A28)

摘　　要：目的了解嘉善县成人病毒性腹泻病原的流行特征。方法采集2014年6月-2015年5月在嘉善县第一人民医院肠道门诊就诊患者的粪便标本;采用实时荧光逆转录PCR法检测标本中轮状病毒(RV)、诺如病毒Ⅰ型(NV GⅠ)、诺如病毒Ⅱ型(NV GⅡ)和星状病毒(Ast V)核酸,并对结果和患者信息进行统计分析。结果共收集408份标本,肠道病毒总阳性率为31.62%,NV GⅡ阳性率最高(28.19%),其次为RV(3.19%),NV GⅠ未检出;检出病毒构成中,NV GⅡ占比最高(87.79%);男性不同年龄段检出率差异有统计学意义(χ2=15.38,P<0.05),40岁~49岁检出率最高(55.56%),<20岁最低(11.76%);病毒检出高峰在4月和12月,6月无阳性检出。结论 NV GⅡ是嘉善县病毒性腹泻主要病原,成人各年龄段都可感染,应加强冬春季病毒性腹泻疾病的监测。Objective To understand the epidemic characteristics of viral diarrhea in adults in Jiashan County. Methods Stool specimens were collected from outpatients in the First People＇s Hospital of Jiashan from June 2014 to May 2015. Rotavirus （RV）, norovirus GI, GII and astrovirus （AstV） were detected by real -time RT -PCR method from nucleic acid, and then the etiological results and patient information were statistically analyzed. Results In a total of 408 stool specimens, the positive rate was 31.62%. Positive rates of norovirus GII was the highest（28.19% ） and followed by rotavirus（3.19% ）. No norovirus GI was detected. The highest proportion of NV G II （87.79%） was detected in the virus. Ages of all patients showed no differ- ence（xz = 10.84, P 〉 0.05）. The detection rate difference in male at different ages were statistically significant （Xz = 15.38, P 〈0.05）, male patients group aged from 40 to 50 had the highest detection rate （55.56%）, and male patients with age 〈 20 years had the lowest rate（ 11.76% ）. The peak of positive rate appeared in April and December and no positive sample was detected in June. Conclusion Norovirus GII is the most common pathogen causing viral diarrhea in Jiashan County which can infect different age groups among adults. The monitoring of viral diarrhea in winter and spring should be strengthened.

关 键 词：病毒性腹泻 流行特征 诺如病毒 

分 类 号：R181.3[医药卫生—流行病学]