妊娠期高血压疾病患者凝血功能及D-二聚体水平检测的临床意义  

Clinical significance of coagulation function and D-dimer level detection in gestational hypertension patients

作　　者：魏蔚[1] 

机构地区：[1]东莞市长安医院妇产科,523843

出　　处：《中国实用医药》2017年第8期41-43,共3页China Practical Medicine

摘　　要：目的分析妊娠期高血压疾病患者凝血功能及D-二聚体(D-D)水平检测的临床意义。方法选择50例妊娠期高血压疾病患者为实验组,另将同期收治的50例健康妊娠孕妇设置为常规组,对比两组的凝血功能及D-二聚体水平。结果实验组的凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)分别为(13.86±2.85)、(10.22±2.55)、(27.84±5.98)s,明显低于常规组的(15.88±3.21)、(12.56±2.68)、(31.85±6.21)s;实验组D-二聚体与纤维蛋白原(FIB)分别为(1.85±0.62)mg/L、(4.68±1.24)g/L,明显高于常规组的(1.32±0.46)mg/L、(3.74±1.20)g/L;差异均有统计学意义(P<0.05)。结论进行D-二聚体与凝血功能指标水平检测的临床意义重大,可及时发现妊娠期高血压疾病患者凝血功能异常情况与高血压疾病,从而指导疾病的治疗。Objective To analyze the clinical significance of coagulation function and D-dimer（D-D） level detection in gestational hypertension patients. Methods There were 50 gestational hypertension patients as experimental group, and concurrent 50 healthy pregnancy women as conventional group. Comparison were made on coagulation function and D-dimer level in two groups. Results The experimental group had thrombin time（TT）, prothrombin time（PT）, activated partial thromboplastin time（APTT） respectively as（13.86±2.85）,（10.22±2.55） and（27.84±5.98） s, which were obviously lower than（15.88±3.21）,（12.56±2.68） and（31.85±6.21） s in conventional group. The experimental group had D-dimer and fibrinogen（FIB） respectively as（1.85±0.62） mg/L and（4.68±1.24） g/L, which were obviously higher than（1.32±0.46） mg/L and（3.74±1.20） g/L in conventional group, and their difference had statistical significance（P〈0.05）. Conclusion Detection of coagulation function and D-dimer level shows great clinical significance, and it can timely finds coagulant function abnormality and hypertension disease in gestational hypertension patients to guide the treatment of disease.

关 键 词：妊娠期高血压 凝血功能 D-二聚体 检测 

分 类 号：R714.246[医药卫生—妇产科学]