检测稳定期慢性阻塞性肺疾病患者呼出气一氧化氮水平的临床意义  

Clinical significance of fractional exhaled nitric oxide （FeNO） in COPD stable condition

作　　者：崔德月 杜晓秋[1] CUI De-yue DU Xiao-qiu(Department of Respiratory Diseases the First People, s Hospital of Changzhou 213003,Jiangsu)

机构地区：[1]常州市第一人民医院呼吸科,江苏常州213003

出　　处：《常州实用医学》2017年第2期71-73,共3页CHANGZHOU PRACTICAL MEDICINE

摘　　要：目的评价检测稳定期慢性阻塞性肺疾病（COPD）患者呼出气一氧化氮水平（FeNO）的临床意义。方法选取COPD稳定期患者80例，健康人87例，分别进行肺功能及FeNO检测，比较稳定期COPD患者与健康人FeNO水平。结果FeNO值COPD患者为17．6±10．5ppb，正常人为20．6±15．7ppb，两组差异无统计学意义（P〉0．05）；FeNO值COPD患者不吸烟组为16．6±7．gppb，正常人不吸烟组为22．4±12．3ppb，两者差异具有统计学意义（P〈0．05）。结论FeNO检测对稳定期COPD患者无诊断价值，稳定期COPD不吸烟患者FeNO值明显低于健康人不吸烟者。Object To explore the clinical significance of FeNO detection in stable COPD patients. Methods A total of 80 patients with stable COPD and 87of healthy people had finished detected lung function and FeNO test. Meanwhile the FeNO level were to be compared between this two gruops. Results （1）The average FeNO of COPD were（17.6±10.3）ppb and healthy people were 20.6±15.7ppb, which had no statistical difference（P=0.14〉0.05）. （2）The average FeNO of no-smokers COPD 16.6±7.4 ppb and no-smokers healthy people were 22.4± 12.3 ppb, which had statistical difference P 〈 0.05. Conclusion FeNO detection played no important role in the judgement for stable COPD patients, but the average FeNO of no-smokers stable COPD patients were significantly lower than no-smokers healthy people.

关 键 词：检测 稳定期慢性阻塞性肺疾病 一氧化氮 临床意义 

分 类 号：R446.1[医药卫生—诊断学]