吸入用布地奈德混悬液治疗妊娠期哮喘的疗效观察  

Observation on Efficacy of Budesonide Suspension Inhalation in Treatment of Asthma in Pregnancy Patients

作　　者：饶智明 王泳晓 徐思恩 陈惠兰 RAO Zhiming WANG Yongxiao XU Si＇ en CHEN Huilan(Dept. of Pharmacy, Zhaoqing Traditional Chinese Medicine Hospital, Guangdong Zhaoqing 526020, China Dept. of Obstetrics and Gynecology, Zhaoqing Traditional Chinese Medicine Hospital, Guangdong Zhaoqing 526020, China)

机构地区：[1]肇庆市中医院药剂科,广东肇庆526020 [2]肇庆市中医院妇产科,广东肇庆526020

出　　处：《中国医院用药评价与分析》2017年第4期509-510,513,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨吸入用布地奈德混悬液治疗妊娠期哮喘的疗效。方法:选取2013年6月—2016年5月肇庆市中医院收治的妊娠期哮喘患者92例作为研究对象,以随机数字表法分为观察组和对照组,每组46例。对照组患者给予常规方法治疗,观察组患者在对照组的基础上加用吸入用布地奈德混悬液治疗。观察两组患者的临床疗效,比较两组患者治疗前后最大呼气流量(PEF)、1s用力呼气容积(FEV1)及临床症状消失时间。结果:观察组患者的总有效率明显高于对照组;观察组患者喘息、哮鸣音等临床症状消失时间均明显短于对照组,差异均有统计学意义(P<0.05)。治疗前,两组患者PEF、FEV_1的差异无统计学意义(P>0.05);治疗后,观察组患者PEF、FEV_1均明显优于对照组,差异均有统计学意义(P<0.05)。结论:吸入用布地奈德混悬液治疗妊娠期哮喘的疗效确切,起效快,能有效改善患者呼吸功能。OBJECTIVE：To probe into the efficacy of budesonide suspension inhalation in treatment of asthma in pregnancy patients. METHODS： 92 pregnancy patients with asthma admitted into Zhaoqing Traditional Chinese Medicine Hospital from Jun. 2013 to May 2016 were selected to be divided into observation group and control group via the random number table, with 46 cases in each. The control group was treated with routine methods, while the observation group was additionally given budesonide suspension inhalation based on the control group. The clinical efficacy was observed, PEF, FEV1 level and disappearance time of clinical symptoms of two groups were compared. RESULTS：The total effective rate of observation group was significantly higher than that of control group; the disappearance time of gasp, wheezing rale in observation group were significantly shorter than those in control group, with statistically significant difference （ P 〈 0. 05 ）. Before treatment, there was no statistical significance between two groups in PEF,FEV1 level（P 〉0. 05）. After treatment, PEF, FEV1 level in observation group were significantly better than those in control group, with statistically significant difference （P〈 0. 05）. CONCLUSIONS：The efficacy of budesonide suspension inhalation in treatment of asthma in pregnancy patients is accurate with fast effects, and can effectively improve patients＇ respiratory function.

关 键 词：布地奈德 雾化吸入 妊娠 哮喘 

分 类 号：R974[医药卫生—药品]