2013-2016年重庆市公共卫生医疗救治中心抗结核药应用分析  

Analysis on Application of Antitubercular Agents in Chongqing Public Health Medical Rescue Centre During 2013-2016

作　　者：王丽[1] 张蓉[1] 张先华 WANG Li ZHANG Rong ZHANG Xianhua(Dept. of Pharmacy, Chongqing Public Health Medical Center, Chongqing 400036, China Dept. of Pharmacy, Chongqing Liujiang Medical Technology Co. , Ltd. , Chongqing 401338, China)

机构地区：[1]重庆市公共卫生医疗救治中心药剂科,重庆400036 [2]重庆柳江医药科技有限公司制剂部,重庆401338

出　　处：《中国医院用药评价与分析》2017年第4期540-542,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解重庆市公共卫生医疗救治中心(以下简称"我院")抗结核药使用情况及趋势。方法:对2013—2016年我院抗结核药的使用情况进行回顾性分析,统计抗结核药的种类、销售金额、用药频度、限定日费用等指标。结果:2013—2016年我院抗结核药的销售金额分别为8 285 913、9 535 327、10 792 168、11 783 654元,呈逐年增长趋势。2013—2016年注射用利福平、利福布汀胶囊的销售金额排序均在前2位之列;2013—2015年对氨基水杨酸异烟肼片的销售金额排序均居第3位,但2016年被吡嗪酰胺片取代。4年来,用药频度排序均居前4位的抗结核药依次为异烟肼片、盐酸乙胺丁醇胶囊、吡嗪酰胺片、利福平胶囊,均为一线口服抗结核药;限定日费用排序居前3位抗结核药依次为注射用利福平、利福平注射液、注射用硫酸卷曲霉素。结论:我院抗结核药的使用仍以一线口服药物为主,其他类抗结核药的使用有逐年增长趋势,结核病疫情不容乐观。OBJECTIVE：To investigate the application and its tendency of antitubercular agents in Chongqing Public Health Medical Rescue Centre （hereinafter referred to as ＂ our hospital ＂）. Methods： The application of antitubercular agents in our hospital from 2013 to 2016 was retrospectively analyzed in terms of species, consumption sum, defined daily dose system （DDDs） and defined daily cost （DDC）. RESULTS： The consumption sum of antitubercular agents were respectively 8 285 913 yuan,9 535 327 yuan, 10 792 168 yuan, 11 783 654 yuan from 2013 to 2016, showed an increasing tendency. The comsumption sum of rifampicin injection and Rifabutin capsules ranked top 2 from 2013 to 2016; the consumption sum of Aminosalicylate isoniazid tablets ranked No. 3 from 2013 to 2015, which was replaced by Pyrazinamide tablets in 2016. All the top four first-line oral antitubercular agents ranked by DDDs were respectively Isoniazide tablets, Ethambutol hydrochloride capsules, Pyrazinamide tablets and Rifampicin capsule during the four years. The top three antitubercular agents ranked by DDC were respectively rifampicin for injection, rifampicin injection and capreomycin sulfate for injection. CONCLUSIONS ： The application of antitubercular agents in our hospital is mainly first-line oral drugs, with increasing tendency of other types of antitubercular agents year by year, and the epidemic situation of tuberculosis is not optimistic.

关 键 词：抗结核药 用药频度 限定日费用 

分 类 号：R978.3[医药卫生—药品]