泻黄散合消风散联合除湿止痒软膏治疗脾胃湿热型糜烂性唇炎临床观察  

Influence of Xiehuang Powder Combined with Xiaofeng Powder and Chushi Zhiyang Ointment in Treatment of Erosive Cheilitis with Damp Heat in Spleen and Stomach Syndrome

作　　者：徐文静[1] 席建元[2] 高亚[2] XU Wenjing XI Jianyuan GAO Ya(Hunan University of Chinese Medicine, Changsha, Hunan 410208, Chinna The First Affiliated Hospital of Hunan University of Chinese Medicine , Changsha, Hunan 410007, China)

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《湖南中医药大学学报》2017年第5期533-535,共3页Journal of Hunan University of Chinese Medicine

摘　　要：目的观察泻黄散合消风散联合除湿止痒软膏治疗脾胃湿热型糜烂性唇炎的临床疗效及复发情况。方法将符合糜烂性唇炎(脾胃湿热型)诊断标准的60例患者采用随机数字表法分为治疗组与对照组各30例。治疗组口服中药泻黄散合消风散加减,唇部外用除湿止痒软膏;对照组单纯使用除湿止痒软膏局部外涂。两组疗程均为4周。以患者唇部皮损面积大小、充血水肿、局部瘙痒灼热感、糜烂流水及结痂作为观察指标并记录治疗前后的积分情况,同时对治愈患者进行6个月的随访。结果两组治疗后的症状积分均较治疗前显著下降(P<0.05),且治疗组的积分下降幅度较对照组明显(P<0.05)。治疗组总有效率为90.0%,对照组为56.7%,治疗组的疗效优于对照组(P<0.05)。治疗组复发率为11.8%,低于对照组的55.6%(P<0.05)。结论泻黄散合消风散联合除湿止痒软膏治脾胃湿热型糜烂性唇炎疗效确切,复发率低,无明显不良反应,值得临床推广应用。Objective To observe the clinical effects and relapses of Xiehuang powder combined with Xiaofeng powder and Chushi Zhiyang ointment in treatment of heat-wet in spleen and stomach type erosive cheilitis. Methods The 60 patients with erosive cheilitis were assigned equality in a randomized way to the treatment group and the control group, 30 cases ineach group. The treatment group were treated with Xiehuang powder combined with Xiaofeng powder and Chushi Zhiyangointment, and the control group were treated with Chushi Zhiyang ointment only. The therapeutic course of both groups was for four weeks. The area and severity index of skin lesions before and after treatment were observed and socored, as well as 6 months follow -up study to all of whom have been cured. Results The scores dramatically decreased after treatment in both groups （P〈0.05）, however the decrement in treatment group was more remarkable than that in control group （P〈0.05）. Thetotal clinical effective rates in these two groups were 90.00% and 56.67%, respectively. Thus, the total effective rate in treat-ment group was significantly superior to that in control group （P〈0.05）. At the same time, the overall recurrence rates in two groups were 11.76% and 55.56%, respectively. The relapse in treatment group was less than that in control group （P〈 0.05）. Conclusion The effect of Xiehuang powder combined with Xiaofeng powder and Chushi Zhiyang ointment in the treat-ment of heat-wet in spleen and stomach type erosive cheilitis is with high security and low relapse rate, and this method is worthy of popularisation and application.

关 键 词：糜烂性唇炎 脾胃湿热 泻黄散 消风散 除湿止痒软膏 临床观察 

分 类 号：R256.39[医药卫生—中医内科学] R781.56[医药卫生—中医学]