冠心病合并糖尿病患者冠状动脉血管内超声特点分析  

Analysis of intravascular ultrasound characteristics of coronary heart disease with diabetes mellitus

作　　者：李志国 纪征[2] 安浩君 陈文生[2] 杨立明[2] 文硕望 张攀 

机构地区：[1]华北理工大学研究生学院,河北省唐山市063000 [2]唐山工人医院心内一科,河北省唐山市063000

出　　处：《临床合理用药杂志》2017年第13期10-12,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的分析冠心病合并糖尿病患者冠状动脉血管内超声影像特点。方法将冠心病患者141例依据是否合并糖尿病分为观察组(合并糖尿病)51例和对照组(无糖尿病)90例,所有患者均于冠脉造影检查后行血管内超声检查,利用血管内超声观察2组病变血管特征。结果观察组三支病变明显多于对照组,单支病变少于对照组,差异有统计学意义(P<0.05);2组双支病变发生率比较差异无统计学意义(P>0.05)。2组斑块类型比较差异无统计学意义(P>0.05)。观察组合并钙化比例高于对照组,病变血管最小管腔面积(MLA)明显小于对照组,斑块负荷(PB)大于对照组,差异均有统计学意义(P<0.05)。结论冠心病合并糖尿病患者病变血管MLA更小,钙化更常见,斑块负荷重,管腔狭窄更弥漫、更严重。Objective To investigate the characteristics of intravascular ultrasound in patients of coronary heart disease complicated with.Methods After coronary angiography,141 patients with coronary heart disease were enrolled in this study,and divided into two groups,according to with or without diabetes mellitus,observation group（diabetes mellitus） 51 cases,control group（without diabetes mellitus） 90 cases,IVUS were applied in all patients.Results The three lesions of observation group were significantly more than control group,a single lesion was less than control group,the difference was statistically significant（P〈0.05）.The incidence of double-vessel disease was similar（P〉0.05）.There was no significant difference in plaque type between two groups（P〉0.05）.The ratio of calcification in observation group was higher than that of control group,the MLA of lesion was significantly smaller than that of control group,the plaque load（PB） was higher than that of control group,the difference was statistically significant（P〈0.05）.Conclusion Patients with coronary heart disease and diabetes mellitus has more severe coronary lesions,bigger PB and smaller MLA compared to patients without diabetes.

关 键 词：冠心病 糖尿病 血管内超声 

分 类 号：R541.4[医药卫生—心血管疾病] R587.1[医药卫生—内科学]