1例化疗致中性粒细胞缺乏伴发热患者的药学监护  

Pharmaceutical care in chemotherapy-induced febrile neutropenia-a case study

作　　者：杨培[1] 缪玮[2] 魏晓晨[3] 

机构地区：[1]天津市中医药研究院附属医院,天津300120 [2]天津医科大学附属肿瘤医院,天津300060 [3]天津市第一中心医院,天津300192

出　　处：《天津药学》2017年第2期22-25,共4页Tianjin Pharmacy

摘　　要：目的:探讨临床药师在化疗所致中性粒细胞缺乏伴发热患者药学监护中的作用。方法:根据《2012年中国中性粒细胞缺乏伴发热患者抗菌药物临床应用指南》、《美国感染协会(IDSA)制定的中性粒细胞减少肿瘤患者抗菌药物应用临床实践指南》、《ASCO白细胞生长因子应用指南》等,对1例肺癌化疗后致中性粒细胞缺乏伴发热患者的诊治全过程进行分析。结果:临床药师从患者化疗方案的选择与调整、骨髓抑制的诊治及抗感染药物的选择与应用等多方面进行药学监护。结论:临床药师在促进患者合理用药、协助医师制定个体化给药方案等方面发挥积极作用。Objective ： To explore the role of clinical pharmacists in pharmaceutical care for a patient with febrile neutropenia after chemotherapy. Methods： According to the guidelines, such as “Antimicrobial Clinical Application in Patients with Fever and Neutropenia： A Chinese Guideline in 2012” ,“ Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy： American Society of Clinical Oncology Clinical Practice Guideline” and “2006 Update of Recommendations for the Use of White Blood Cell Growth Factors ： An Evidence - Based Clinical Practice Guideline” , the service provided by clinical pharmacists in the course from diagnosis till the whole treatment in a patient with of lung cancer and chemotherapy - induced febrile neutropenia was followed and analyzed. Results ： Clinical pharmacists performed pharmaceutical care in chemotherapy drug selection and adjustment, diagnosis and treatment process of bone marrow suppression, antimicrobial selection and application and et al. Conclusions ： Clinical pharmacists can play a positive role in promoting the rational use of drugs, helping physician make individualizde regimens and others.

关 键 词：中性粒细胞缺乏伴发热 化疗 药学监护 临床药师 

分 类 号：R969.3[医药卫生—药理学]