从肾虚血瘀理论探讨类风湿关节炎的发病机制  

Pathogenesis of Rheumatoid Arthritis From Deficiency of Kidney and Blood Stasis

作　　者：李蓉[1] 宁乔怡 姚血明[1] 樊赟[1] 周静[1] 候雷[1] 马武开[1] 

机构地区：[1]贵阳中医学院,贵州贵阳550001

出　　处：《中华中医药学刊》2017年第5期1206-1208,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81360580);贵州省社会发展攻关计划项目(黔科合SY[2010]3102号);贵州省省长基金项目[黔省专合字(2012)33];贵州省科技创新人才团队项目[黔科合人才团队(2013)4033]

摘　　要：类风湿关节炎(rheumatoid arthritis,RA)的免疫炎症反应和骨破坏伴随其整个病程,是导致关节畸形和功能障碍的主要原因。根据RA的病情特点,以中医"肾主骨生髓、多虚多瘀"理论为指导,分析肾虚血瘀病机与RA病程中的相关性,探讨补肾活血法延缓RA病情的重要机制,为运用补肾活血法治疗RA提供理论依据。The immune inflammation and bone destruction as the leading cause of the joint deformity and dysfunction are throughout the whole course of rheumatoid arthritis （RA）. This article based on the characteristics of RA, guided by the theory of traditional Chinese medicine that kidney determing the condition of the bone and marrow and is susceptibility to deficiency and stasis, analyzes the correlation between the pathogenesis of kidney deficiency and blood stasis with the course of RA to explore the important mechanism to delay the disease by the therapy of strengthening kidney and activa- ting circulation and provide the theoretical basis for using the therapy of strengthening kidney and activating circulation in the treatment of RA.

关 键 词：痹证 类风湿关节炎 炎症 肾虚血瘀 补肾活血 病因病机 

分 类 号：R593.22[医药卫生—内科学]