大脑中动脉闭塞FLAIR血管高信号征的血流动力学研究  

The Study on the Hemodynamics of FLAIR Hyperintensity in Acute Ischemic Stroke Patients with Middle Cerebral Artery Occlusion

作　　者：李婵婵[1] 杨艳梅[1] 尹乐康[1] 张晓雪[1] 郝霄竹 田家齐[1] 姚振威[1] 冯晓源[1] 

机构地区：[1]复旦大学附属华山医院放射科

出　　处：《中国医学计算机成像杂志》2017年第2期107-112,共6页Chinese Computed Medical Imaging

基　　金：国家自然科学基金;No.81371521~~

摘　　要：目的:探讨大脑中动脉闭塞(MCAO)急性缺血性卒中患者远段FLAIR血管高信号征(FVH)的血流动力学基础。方法:对38例CTA诊断的单侧MCAO急性缺血性卒中患者于发病3天内行MRI和CTP检查。评价MRI T2-FLAIR序列上FVH的显示,分为无远段FVH和远段FVH两组;评价CTP原始图像患侧代偿血流充盈情况,分为无代偿血流、代偿血流充盈顺序混乱和代偿血流逆向逐渐充盈三组;比较FVH的显示与CTP原始图像患侧代偿血流充盈情况。结果:38例单侧MACO急性缺血性卒中患者,16例无远段FVH,其中5例CTP原始图像患侧无代偿血流,6例代偿血流充盈顺序混乱;22例远段FVH,CTP原始图像患侧均显示代偿血流逆向逐渐充盈;共33例患者(86.8%)FVH的显示和CTP原始图像患侧代偿血流(即侧支循环)充盈情况相符。结论:MCAO急性缺血性卒中患者远段FVH的形成可能源于侧支循环。Purpose： To investigate the hemodynamics of distal FLAIR vascular hyperintensity （FVH） in acute ischemic stroke patients with middle cerebral artery occlusion （MCAO）. Methods： MRI and CT perfusion （CTP） were performed within 3 days of symptom onset in 38 acute ischemic stroke patients with MCAO. The images of MRI T2- FLAIR were dichotomized into no distal FVH and distal FVH groups. The ipsilateral collateral circulation was assessed by CTP and classified into no collateral circulation, collateral circulation confusedly filling and collateral circulation gradually reverse filling three categories. The display of FVHs and the condition of ipsilateral collateral circulation were compared. Results： Of 16 patients with no distal FVH, 5 were classified as no collateral circulation and 6 were classified as collateral circulation confusedly filling. All of the 22 patients with distal FVH were classified as collateral circulation gradually reverse filling. In conclusion, there were 33 patients （86.8%） whose FVHs match the condition of ipsilateral collateral circulation on CTP original images. Conclusion： The distal FVH in acute ischemic stroke patients with MCAO may relate to the collateral circulation.

关 键 词：磁共振成像 大脑中动脉闭塞 卒中 侧支循环 

分 类 号：R445.2[医药卫生—影像医学与核医学]