乙肝后肝硬化门静脉高压症外周血细胞计数与脾内静脉血细胞计数的对比分析  

Comparative analysis of cirrhosis and portal hypertension peripheral blood count and splenic vein blood cell counts of patients with hepatitis B related cirrhosis

作　　者：华江[1] 严志涵[2] 

机构地区：[1]江苏省苏州市立医院北区检验科,215008 [2]江苏省无锡市第五人民医院肝病科,214005

出　　处：《检验医学与临床》2017年第9期1236-1237,1240,共3页Laboratory Medicine and Clinic

基　　金：南京医科大学科技发展基金项目(2013NJMU197)

摘　　要：目的对比分析乙肝后肝硬化门静脉高压症外周血细胞计数与脾内静脉血细胞计数。方法选择2013年7月至2016年2月接受脾切除术的36例乙肝后肝硬化门静脉高压症患者,手术过程中抽取患者脾门、脾上极及脾下极部位的脾内静脉血,将其血细胞计数对比手术前外周血细胞计数。结果脾内血细胞的白细胞(WBC)、红细胞(RBC)、血小板(PLT)计数与外周血细胞相比升高,差异有统计意义(P<0.05);脾门、脾上极及脾下极部位的WBC、RBC计数相比,差异无统计意义(P>0.05);脾门、脾上极及脾下极部位的PLT计数相比,差异有统计意义(P<0.05);外周血细胞与脾内血细胞之间的RBC、WBC计数无相关性(P>0.05);外周血细胞与脾内血细胞的PLT计数呈正相关(P<0.05)。结论乙肝后肝硬化门静脉高压症患者外周血WBC、PLT计数与脾内静脉血细胞计数降低相关,且外周血细胞与脾内血细胞的PLT计数具有相关性,具有临床实践意义。Objective To analyze the portal hypertension peripheral blood count and splenic vein blood cell counts of patients with hepatitis B related cirrhosis.Methods A total of 36 cases with hepatitis B patients related cirrhosis and portal hypertension who received splenectomy from July 2013 to February 2016 in our hospital were selected.During surgery,spleen venous blood was extracted from splenoportal,splenic upper pole and lower pole of spleen,and the blood counts before surgery were compared with peripheral blood counts.Results White blood cells （WBC）,red blood cells （RBC） and platelet （PLT） in splenic blood were significantly higher than that of peripheral blood cells （P〈0.05）.Differences of WBC and RBC in splenic upper pole,splenoportal and lower pole count didn′t have statistical significance （P〉0.05）.While,differences of PLT in splenic upper pole,splenoportal and lower pole had statistical significance （P〈0.05）.RBC and WBC in peripheral blood cells and spleen cells didn′t have correlation（P〉0.05）.PLT counts in peripheral blood was positively correlated with that in spleen （P〈0.05）.Conclusion WBC and PLT in patients with hepatitis B related cirrhosis and portal hypertension in peripheral blood and splenic vein blood cell count decrease,and PLT counts in peripheral blood is correlated with that in spleen cells,which has clinical significance.

关 键 词：乙肝 肝硬化门静脉高压症 血细胞计数 

分 类 号：R657.34[医药卫生—外科学]