氯胺酮分子印迹聚合物的制备与性能研究  

Studies on preparation and characteristics of ketamine molecularly imprinted polymers

作　　者：文云波[1] 刘鹏[2] 李衍德[2] 任周阳[1] 倪春明[1] 曹秋娥[2] 

机构地区：[1]云南警官学院,云南昆明650223 [2]云南大学化学科学与工程学院,云南昆明650091

出　　处：《化学研究与应用》2017年第5期599-603,共5页Chemical Research and Application

基　　金：公安部重点研究计划项目(201301ZDYJ008)资助;公安部科技强警基础工作专项项目(2013GABJC018)资助

摘　　要：为了制备对氯胺酮具有选择性识别能力的分离富集材料,实验采用本体聚合法,以氯胺酮为模板,(-甲基丙烯酸(MAA)为功能单体,乙二醇二甲基丙烯酸酯(EGDMA)为交联剂,在优化了功能单体与交联剂的用量后,制备了一种吸附性能理想的分子印迹聚合物。该印迹聚合物在氯胺酮浓度为100μg·m L^(-1)的甲醇溶液中对氯胺酮的吸附量为33.8 mg·g^(-1),印迹因子为2.02,而且可以再生与重复使用。A kind of ketamine molecularly imprinted polymers（ MIPs） was prepared for selective separation of ketamine by mass pol-ymerization using ketamine as templet,methacrylic acid（MAA）as function monomer and ethyleneglycol dimethacrylate（ EGDMA） as cross linker. The amounts of the function monomer and cross linker used in polymerization were optimized by studying the binding capacity and selective recognition of the imprinting polymers. The results showed that ketamine-MIP prepared with the ratio of ket-amine ,MAA and EGDMA added as 1 -4-30 not only possessed the highest binding capacity and best selective recognition among all of the MIP synthesized in this experiment, but also possessed reproducibility. The binding capacity and imprinting factor were de-termined as 33. 8 mg · g- 1 and 2. 02 by equilibrium adsorption experiment in 100μg· mL - 1 ketamine solution, respectively.

关 键 词：氯胺酮 分子印迹技术 分子印迹聚合物 吸附 

分 类 号：O658.9[理学—分析化学]