双源CT诊断房间隔病变与隐匿性脑卒中相关性研究  

Correlation between the interauricular septum diseases and cryptogenic ischemic stroke on double source CT

作　　者：刘海峰[1] 蒋宇宏[1] 阳义[1] 刘兴华[1] 蒋鸿[1] 引龙 李维娜[1] 姚雪云 杨昊 

机构地区：[1]武汉市第一医院放射科,湖北武汉430030 [2]武汉市第八医院放射科,湖北武汉430030 [3]湖北省第三人民医院神经内科,湖北武汉430030

出　　处：《实用放射学杂志》2017年第5期684-687,共4页Journal of Practical Radiology

基　　金：湖北省卫生计生科研基金资助项目（WJ2017M181）.

摘　　要：目的 对比分析中青年隐匿性脑卒中（CS）与正常人群卵圆孔未闭（PFO）,房间隔膨出瘤（ASA）,房间隔缺损（ASD）的双源CT检出率及相关危险因素发生率差异.方法 收集168例中青年CS患者及年龄、性别相匹配的180例正常对照者的双源CT冠状动脉检查影像资料及临床检查资料,比较分析2组PFO、ASA、ASD的发生率,PFO及ASD孔径大小,PFO通道长度及CS相关危险因素水平的差异.结果 CS组与正常组PFO、ASA及ASD的检出率分别为40.6%、10.7%、6.5%和15.6%、3.3%、2.2%,差异有统计学意义（P＜0.001）;PFO合并ASA以及ASA合并ASD的检出率分别为6.0%、3.0%和0%、0%,差异有统计学意义（P＜0.001）;2组PFO及ASD孔径大小分别为（1.71±0.62） mm、（3.42±0.72） mm和（0.85±0.51） mm、（2.45±0.42） mm,差异有统计学意义（P＜0.001）;2组PFO通道长度分别为（14.6±3.8） mm和（8.2±2.3） mm,差异有统计学意义（P＜0.001）;2组脑卒中相关危险因素水平的差异无统计学意义（P＞0.001）.结论 PFO、ASA和ASD对中青年CS的发生有重要意义,双源CT冠状动脉成像能够准确诊断PFO、ASA和ASD.Objective To investigate the association and difference between patent foramen ovale（PFO）, atrial septal aneurysm（ASA）, atrial septal defect（ASD） in normal controls and cryptogenic ischemic stroke（CS） in youth diagnosed by double source CT.Methods A total of 168 CS patients and 180 controls matched age and gender were included in the present study.The two groups were diagnosed by double source CT and clinical materials.The incident rate of PFO, ASA, ASD, the degrees of PFO, ASD,the lengths of PFO and difference between CS in two groups were analysed.Results The incident rates of PFO, ASA, ASD were 40.6%,10.7%,6.5% and 15.6%,3.3%,2.2% in CS groups and controls respectively（P〈0.001）.The incident rates of PFO merged ASA and ASA merged ASD were 6.0%,3.0% and 0%,0% respectively between two groups（P〈0.001）.The diameters of PFO, ASD were （1.71±0.62） mm,（3.42±0.72） mm and （0.85±0.51） mm,（2.45±0.42） mm in two groups respectively（P〈0.001）.The lengths of PFO were （14.6±3.8） mm and （8.2±2.3） mm in two groups（P〈0.001）.The correlations between stroke in two groups were no difference（P〉0.001）.Conclusion PFO,ASA and ASD are important to CS.While PFO,ASA and ASD can accurately be diagnosed by double source CT.

关 键 词：隐匿性脑卒中 卵圆孔未闭 房间隔膨出瘤 房间隔缺损 计算机体层成像 

分 类 号：R541[医药卫生—心血管疾病] R814.42[医药卫生—内科学]