Goodpasture综合征的HRCT诊断  

HRCT diagnosis of Goodpasture syndrome

作　　者：刘静[1] 许美 刘秀丽[3] 刘景旺[4] 高义军[5] 

机构地区：[1]华北理工大学附属开滦总医院肾内科,河北唐山063000 [2]唐山市强制隔离戒毒所,河北唐山063000 [3]沧州医学高等专科学校,河北沧州061000 [4]华北理工大学附属开滦总医院CT室,河北唐山063000 [5]华北理工大学附属开滦总医院妇产科,河北唐山063000

出　　处：《实用放射学杂志》2017年第5期726-728,749,共4页Journal of Practical Radiology

摘　　要：目的 探讨Goodpasture综合征的高分辨率CT（HRCT）影像学表现及随访变化特点.方法 回顾性分析本院15例经临床确诊的Goodpasture综合征患者的HRCT表现及随访复查情况.分别记录病变范围、形态及动态变化情况.结果 病变累及2叶1例,累及3叶2例,累及4叶5例,累及5个肺叶7例.右肺上叶最易受累.双侧以肺门为中心分布实变伴边缘磨玻璃密度影（GGO）7例,5例呈双肺弥漫分布GGO.病变实变区短期复查呈GGO改变,GGO能短期吸收.结论 咯血并贫血患者,双肺多叶的肺内实变混杂GGO,不累及肺尖及肺外带胸膜下是Goodpasture综合征的特征性表现.HRCT是Goodpasture综合征诊断和疗效观察的有效手段.Objective To analyze the imaging features and follow-up changes of high-resolution CT（HRCT） in Goodpasture syndrome.Methods HRCT imaging features and follow-up findings of 15 cases Goodpasture syndrome confirmed by clinical were analyzed retrospectrively.The imaging features included extent,forms and follow-up changes.Results The lung lesion of Goodpasture syndrome involved two lobes（n=1）, three lobes（n=2）, four lobes（n=5） and five lobes （n=7）.Upper lobe of the right lung was the most common involved region.Centered on the hilum of lung consolidations confused ground glass opacity （GGO） were showed in 7 cases, GGO distribution of pulmonary leaflets in 5 cases.On follow-up observation, lobar or segmental consolidation could change into GGO,GGO could disappear in short times.Conclusion Multiple lobar or segmental consolidations confused GGO without the lung bottom and periphery involvement is the imaging characteristics of Goodpasture syndrome patients with anemia and hemoptysis.HRCT is a helpful method for the diagnosis and following up of Goodpasture syndrome.

关 键 词：GOODPASTURE综合征 计算机体层成像 

分 类 号：R692[医药卫生—泌尿科学] R814.42[医药卫生—外科学]