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作 者:陈爽[1] 凌华[1] 喻臻[1] 唐云[1] 叶盛[1]
出 处:《预防医学情报杂志》2017年第5期442-446,共5页Journal of Preventive Medicine Information
摘 要:目的了解重庆市2011-2015年流感流行特征及优势毒株的型别分布,为流感防治工作提供科学依据。方法通过收集流行病学资料、核酸检测技术及病毒分离技术,对重庆市2011-2015年流感样病例(ILI)进行流行病学、病原学及统计学分析。结果 2011-2015年重庆市流感样病例百分比(ILI%)为1.15%,ILI%曲线总体走势平稳,各监测年度ILI%有差异(P<0.01)。从年龄上看,ILI在0~4岁组最高(55.29%),在60~岁组最低(2.69%),各年龄组ILI分布有差异(P<0.01)。流感监测核酸阳性率13.29%,暴发阳性率达到66.75%,型别分布均以H3型和B为主,各年份核酸阳性率有差异(P<0.01)。5年共分离到流感毒株2244株,病毒分离率为8.60%。不同哨点医院ILI采样核酸阳性率、不同网络实验室病毒分离率存在差异。结论 2011-2015年重庆市流感活动强度保持平稳,不同亚型流感病毒交替流行,无重大流感疫情发生。坚持开展流感监测工作,对控制流行与预测有重要意义。Objective To understand the epidemiological characteristics and dominant virus types of influenza in Chongqing from 2011 to 2015, and to provide scientific evidence for developing influenza prevention measures. Methods Through collection of epidemiological data, nucleic acid tests and virus isolation, influenza - like ill- ness (ILI) cases in Chongqing from 2011 to 2015 were analyzed from epidemiological, etiological and statistical perspectives. Results From 2011 to 2015, the percent of influenza - like illness (ILI) cases was 1.15% in Chongqing, with an overall steady trend over the period and slight differences in different years ( P 〈 0. O1 ). Seen by age, ILI cases were mostly in the 0 - 4 year group (55.29%) and the least in the 60 - year group (2.69%) ; differences were found in ILI distribution of different age groups ( P 〈0. 01 ). The positive rate of nucleic acid detection was 13.29% , and the positive rate of its outbreak was 66.75% ; H3 and B were the pri- mary types. Positive rates of nucleic acid detection were different in different years ( P 〈0.01 ). 2, 244 influ- enza viruses were isolated over the last five years, and the virus isolate rate was 8.60%. differences were found in the positive rate of the nucleic acid of the ILl samples collected by different sentinel hospitals and in virus isolation rates in different network laboratories Conclusion The predominant strains of influenza were stable in Chongqing from 2011 to 2015. Different subtypes of influenza virus were prevalent in an alternate manner; no major influenza epidemic was occurred. Further strengthen influenza surveillance is essential to the prevention and forecast of influenza.
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