丹参联合人血白蛋白对难治性肝腹水的疗效观察  

Curative Effect of Salvia Injection plus Human Albumin on Refractory Ascites

作　　者：王静[1] 黄忠[1] 魏尉[1] 胡赞芬 

机构地区：[1]自贡市第一人民医院消化内科,四川自贡643000

出　　处：《西南军医》2017年第3期233-236,共4页Journal of Military Surgeon in Southwest China

摘　　要：目的研讨丹参与人血白蛋白联合使用对肝硬化难治性腹水的治疗效果。方法肝硬化难治性腹水的患者共计60例,随机分为治疗组、对照组,各组均30例。两组患者均予保肝、支持治疗。对照组:予螺内酯+呋塞米利尿治疗。治疗组:予以上治疗的同时,予以白蛋白输入+丹参注射液20 m L。观察两组患者肝功、24 h尿量、体质量及腹水治疗的总有效率。结果治疗组患者的以上各检查指标均显著优于对照组,P<0.05,差异具有统计学意义。治疗组患者治疗总有效率(90.0%)显著高于对照组(73.0%),P<0.05,差异有统计学意义。结论在肝硬化难治性腹水治疗中,常规利尿治疗基础上,丹参与人血白蛋白联合使用可有效改善患者临床症状,值得推广。ABSTRACT Objective To discuss the curative effect of salvia injection plus human albumin on refractory cirrhosis ascites. Methods 60 cases with refractory cirrhosis ascites were randomly divided into 2 groups： treatment group and control group, 30 cases in each; the diretic therapy with spironolactone and furosemide was applied to cases in bothgroups while human albumin infusion plus salvia injection were added to cases in treatment group; observation was made to liver function, 24-hour urine volume, body weight of the cases in both groups as well as the total effective rate of ascites. Results The data of the cases in treatment group were much superior to those of the cases in control group and the difference was of statistical significance （ P 〈 0. 05 ） ; the total effective rate in treatment group was 90. 0%, much higher than that in control group （73.0%）, the difference was of statistical significance （ P 〈 O. 05 ）. Conclu- sions The combined application of human albumin and salvia injection in the treatment of refractory cirrhosis ascites besides the routine diuretic therapy can effectively improve the clinical symptoms of the patients, it is worthy of wide clinical application.

关 键 词：丹参注射液 白蛋白 利尿 肝硬化 难治性腹水 

分 类 号：R285[医药卫生—中药学]