猪殃殃药材质量控制方法研究  

Research on quality control method of Galii Aparinis Herba

作　　者：李建晨[1] 白伟红[1] 黑静[1] 槐红微 LI Jianchen BAI Weihong HEI Jing HUAI Hongwei(School of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, Hebei 050018, China)

机构地区：[1]河北科技大学化学与制药工程学院,河北石家庄050018

出　　处：《河北工业科技》2017年第3期162-166,共5页Hebei Journal of Industrial Science and Technology

基　　金：国家"重大新药创制"科技重大专项(2014ZX09304307-002);河北省中药材标准研究项目

摘　　要：为了修订猪殃殃原有标准中关于性状方面的内容,有效反映和控制药材的内在质量,收集了10批猪殃殃药材,对其性状、专属性鉴别、检查项、指标成分含量进行了研究。采用薄层色谱进行定性鉴别,高效液相色谱法测定绿原酸的含量。研究发现:TLC斑点清晰,分离度好;10批样品中水分小于13.0%,总灰分小于16.0%,酸不溶性灰分小于3.5%,醇溶性浸出物小于7.0%,绿原酸质量分数小于0.1%。结果表明:所制定的猪殃殃药材质量控制方法,操作简便,重复性良好,可为猪殃殃药材的全面质量控制提供依据。In order to revise the original Galii Aparinis Herba standard on the nature of the content, and effectively reflect and control the inherent quality of herbs,ten batches of Galii Aparinis Herba are collected. The morphology, identification, inspec-tion and the content of target components in these crude drugs are studied. TLC method is used to identify this crude drug. The contents of chlorogenic acid in these samples are determined by HPLC. The spot of TLC is clear and well-separated. According to the measurement results of the ten samples, moisture is not more than 13. 0%？ total ash is not more than 16. 0% , acid- insolubal ash content is not more than 3. 5% , and alcohol extracts content is not less than 7. 0%. The content of chlorogenic acid is above 0. 1%. The results show that the set of medicinal materials quality control has the characteristics of simple opera-tion and good repeatability, and can provide the basis for the comprehensive quality control of Galii Aparinis Herba.

关 键 词：中药化学 猪殃殃 质量控制方法 绿原酸 含量测定 高效液相色谱法 

分 类 号：TQ46[化学工程—制药化工] R932[医药卫生—生药学]