一种喹啉类Zn^(2+)荧光比率型探针  

Ratiometric Fluorescent Probe Based on a Quinoline for Zn^(2+)

作　　者：陈嘉韵[1] 潘珺仪 陈志[1] 陈梓亮 马立军[1] 

机构地区：[1]华南师范大学化学与环境学院,广州510006

出　　处：《华南师范大学学报（自然科学版）》2017年第2期56-60,共5页Journal of South China Normal University(Natural Science Edition)

基　　金：广东省自然科学基金项目(2015A030313392);广州市珠江科技新星资助项目(2012J2200026)

摘　　要：以8-氨基喹啉为母体,设计并合成一种Zn^(2+)比率型荧光探针,通过核磁、质谱表征其结构.利用荧光光谱、紫外-可见吸收光谱等研究了探针的识别性能.结果表明,该探针在pH为4.0~9.5条件下均能有效识别Zn^(2+),尤其在pH 7.4的生理条件下具有最优的识别能力.探针与Zn^(2+)能形成结合摩尔比为1∶1的稳定络合物且灵敏度高、选择性强、响应迅速,因此该荧光探针具有在生物及环境等领域有效检测Zn^(2+)的潜力.A ratiometric fluorescence probe based on 8-aminoquinoline for Zn2＋ was designed and synthesized. The structure was characterized by 1H-NMR and MS. The properties of this probe were tested by UV-Vis absorption and fluorescence spectra. The results indicated that the probe showed good recognition for Zn2＋in pH 4.0-9.5, es- pecially in pH 7.4, the physiological condition. The probe can combine Zn2＋ to a stable complex at the mole ratio of 1：1. The fluorescence probe showed high sensitivity, excellent selectivity and fast fluorescence response toward Zn2＋. Therefore, the probe has potential to recognize Zn2＋ in the fields of life and environment.

关 键 词：8-氨基喹啉 Zn2+ 荧光探针 

分 类 号：O626.323[理学—有机化学]