危重烧伤致创伤后应激障碍患者临床干预研究  

Clinical intervention in post-traumatic stress disorder following severe burn

作　　者：孙玉军[1] 沙东想 苑光宗[1] 王鹏举[1] 李亚军 

机构地区：[1]昆山昆山市第三人民医院,江苏215311 [2]昆山市康复医院,江苏昆山215311

出　　处：《临床心身疾病杂志》2017年第2期16-19,共4页Journal of Clinical Psychosomatic Diseases

基　　金：昆山市社会发展科技惠民项目（编号KS1625）

摘　　要：目的探讨舍曲林联合一般支持性心理治疗对危重烧伤致创伤后应激障碍患者的临床疗效，为临床诊治提供依据。方法对17例危重烧伤致创伤后应激障碍患者予以舍曲林联合一般支持性心理治疗，观察6个月。于干预前后采用创伤后应激障碍平民版筛查问卷、症状自评量表、焦虑自评量表、抑郁自评量表进行测评分析。结果本组患者干预后创伤后应激障碍平民版筛查问卷、症状自评量表、焦虑自评量表、抑郁自评量表评分均较干预前显著降低（P〈0．05或0．01）。相关分析显示，创伤后应激障碍平民版筛查问卷总分干预前与症状自评量表总均分呈显著正相关（P〈0．05），干预后与症状自评量表总均分、焦虑自评量表总分、抑郁自评量表总分呈显著正相关（P〈0．05或0．01）。结论舍曲林联合一般支持性心理治疗能显著改善危重烧伤致创伤后应激障碍患者的创伤后应激障碍症状及焦虑、抑郁症状，值得临床推广应用。Objective To the efficacy of sertraline plus general supportive psychotherapy （GSP） in posttraumatic stress disorder （PTSD） following severe burn in order to provide basis for clinical diagnosis and treatment. Methods Seventeen patients with PTSD following severe burn were treated with sertraline plus GSP for 6 months. Assessments were performed with the PTSD Checklist-Civilian Version （PCL-C）, Symptom Checklist-90 （SCL-90）, Self-rating Anxiety Scale （SAS） and Self-rating Depression Scale （SDS） before and after intervention. Results After intervention the PCL-C, SCL-90, SAS and SDS score lowered more significantly compared with pre-intervention （P 〈0.05 or 0.01）. Correlation analysis showed that pre-intervention total PCL C score was positively related to total SCL-90 score significantly （P 〈0.05） and post-intervention to total SCL-90, SAS and SDS （P 〈0.05 or 0.01）. Conclusion Sertraline combined with GSP cpuld notably improve the symptoms of PTSD, anxiety and depression and the devel opment of comorbid anxiety and depression should be prevented.

关 键 词：危重烧伤 创伤后应激障碍 舍曲林 心理治疗 

分 类 号：R644.749.5[医药卫生—外科学]