隐匿性乙型肝炎病毒感染研究进展  

Progress in research of occult hepatitis B virus infection

作　　者：黄象艳[1] 石庆芬[2] 黄涛[3] 

机构地区：[1]济南军区总医院输血科,250031 [2]济南市传染病医院检验科,250021 [3]山东省疾病预防控制中心艾滋病防治所,济南250014

出　　处：《中华流行病学杂志》2017年第5期688-692,共5页Chinese Journal of Epidemiology

基　　金：国家自然科学基金（81101321）

摘　　要：隐匿-HBV感染（OBI）已成为世界性公共卫生问题之一，严重影响乙型肝炎的临床诊断并威胁到输血安全。本文分析近年来关于OBI的概念、致病机制、在健康人群和不同患者中的流行率以及传播可能性方面的研究数据，结果显示OBI在健康人群及不同患者中均存在一定的流行率，并可能通过输血等途径传播，应引起重视。Occult hepatitis B virus infection is a worldwide public health problem, which seriously affects the clinical diagnosis of hepatitis B and threatens the safety of blood transfusion. The concept of occult hepatitis B virus infection, the pathogenesis of occult hepatitis B virus infection, the prevalence of occult hepatitis B virus infection in different groups, including healthy population and different patients, and the possibility of transmission were summarized. The prevalence of occult hepatitis B virus infection was found in healthy population and different patients, and there is possibility of occult hepatitis B virus infection to be transmitted through blood transfusion. The paper provides a comprehensive introduction of the pathogenesis and prevalence of occult hepatitis B virus infection. More attention should be paid to occult hepatitis B virus infection.

关 键 词：隐匿性乙型肝炎病毒感染 致病机制 流行率 

分 类 号：R512.62[医药卫生—内科学]