1999-2015年连云港市肾综合征出血热流行特征分析  

Analysis of theepidemiological characteristics of hemorrhagic fever with renal syndrome in Lianyungang City between 1999 and 2015

作　　者：辛化雷[1,2] 张永杰[3] 祖荣强[3] 胡建利[3] 孙军玲[2] 裴迎新[2] 张云[4] 岳明[5] 王笑辰 

机构地区：[1]青岛市疾病预防控制中心,山东青岛266000 [2]中国疾病预防控制中心 [3]江苏省疾病预防控制中心,江苏南京210000 [4]南京军区军事医学研究所,江苏南京210000 [5]南京医科大学第一附属医院,江苏南京210000

出　　处：《现代预防医学》2017年第10期1734-1738,共5页Modern Preventive Medicine

基　　金：国家自然科学基金项目(81473036);江苏省重大新发传染病综合防控科技示范工程(BE2015714);江苏省流行学重点学科(ZDXKA2016008);江苏省医学青年人才项目(QNRC2016545)

摘　　要：目的了解江苏省连云港市肾综合征出血热(HFRS)流行特征,为该市HFRS防制提供科学依据。方法采用描述性流行病学方法对1999-2015年江苏省连云港市HFRS的时间、地点和人群分布情况进行描述。结果 1999-2015年连云港市共报告1 937例HFRS病例,占全省总数的32.6%,年均发病率2.34/10万,1999-2015年发病率总体呈下降趋势;呈秋冬型单峰分布,10月-次年1月病例数占总数的75.5%,不同县区发病高峰存在差异;年均发病率以灌云县最高,为3.92/10万,赣榆县HFRS发病率由1999年的12.93/10万下降到2015年0.34/10万、东海县由4.91/10万下降到0.74/10万,市区(海州、连云)发病2001年之前最低0.15/10万,2013-2015年最高达到4.07/10万;随年龄增大发病率上升,60岁~发病率最高,为6.33/10万,60岁以上年龄组2005-2008年发病率在3.61/10万以下,2009-2015年(除2012年)在4.69~6.86/10万之间。结论连云港市HFRS流行近年出现老疫区(赣榆、东海)发病率降低,而市区(海州、连云)上升,60岁以上年龄组发病上升的新特征,需要及时调整防控重点。Objective The study aimed to assess the epidemiological characteristics of hemorrhagic fever with renal syndrome （HFRS） in Lianyungang City, and thus to provide scientific reference for the prevention and control of HFRS.Methods Descriptive epidemiological method was used to analyze the time, location, population distribution of HFRS.Results A total of 1937HFRS cases were reported in Lianyungang City between 1999 and 2015, accounted for 32.6% of the total cases in the Province. The annual average incidence was 2.34/100 000, showing a declining trend from 1999 to 2015. The distribution showed a single-peak in autumn and winter. The case amount from October to the January of the next year accounted for 75.5% of the total amount, and onset peaks were different in different counties and districts. The annual average incidence of Guanyun County ranked the top （3.92/100 000）. The incidence of HFRS in Ganyu County declined from 12.93/100 000 of 1999 to 0.34/10 000 of 2015, and the incidence in Donghai County declined from 4.91/100 000 to 0.74/10 000.The minimal incidence in the urban area （Haizhou, Lianyun） before 2001 was 0.15/100000, the incidence peaked in 2013-2015 with 4.07/ 100000.The incidence of the population above the age of 60 ranked the top among all populations （6.35/100 000）, and was below 3.61/100000 in 2008 and between 4.69-6.86/100000 between 2009 and 2015 （excl. 2012）.Conclusion HERS epidemics in Lianyungang City showed a declining trend of incidence in old epidemic areas （Ganyu, Donghai）, but a rising trend in the urban area （Haizhou, Lianyun）. For new characteristics of increased incidence in the population above the age of 60, key prevention and control points should be adjusted timely.

关 键 词：肾综合征出血热 流行特征 连云港 

分 类 号：R181.22[医药卫生—流行病学]