7-羟基-4-甲基香豆素的合成及其荧光性质研究  

Synthesis of 7-hydroxy-4-methyl-2H-chromen-2-one and Its Fluorescent Property

作　　者：陈爱乾 侯慧静[1] 唐大梅[1] 胡云[1] 

机构地区：[1]遵义医学院珠海校区生物工程系,广东珠海519041

出　　处：《广东化工》2017年第9期91-92,共2页Guangdong Chemical Industry

基　　金：贵州省教育厅青年自然科学研究项目(黔教合KY[2014]302号);遵义医学院博士科研启动资金(F709)

摘　　要：很多香豆素具有多种生物活性,同时也具有优良的荧光性能。本论文以间苯二酚和乙酰乙酸乙酯为原料,在微波辅助下合成了一种简单香豆素——7-羟基-4-甲基香豆素(C1)。荧光性质研究结果显示,C1的荧光性质受溶剂的极性及pH等因素影响较大。在极性较大溶剂中,C1荧光的最大激发波长及发射波长均发生红移,在pH值较大的碱性条件下,其荧光强度明显增大。Many coumarin derivatives have various biological activities and also maintain favorable flouresent property. In this work, a simple coumarin 7-hydroxy-4-methyl-2H-chromen-2-one （C1） was synthesized from the starting material m-dihydroxybenzene and Ethyl acetoacetate under the microwave irradiation Evidences showed that the fluoresent property of CI were noticeably influenced by the polarity and pH of solvents, In polar solvents, the max excited and emission λ were red shifted, and the fluoresent intensity markly increased in alkaline condition.

关 键 词：香豆素 荧光性质 化学合成 

分 类 号：TQ422[化学工程]