多囊肾合并颅内动脉瘤性蛛网膜下腔出血2例临床分析并文献复习  

Analysis of treatment and review of literature in two patients with autosomal-dominant polycystic kidney disease accompanied aneurysmal subarachnoid hemorrhage

作　　者：闵杰[1] 吴明灿[1] 姚远[1] 杨磊[1] 赵健[1] 王仙[1] 陈世洁[1] 

机构地区：[1]荆州市第一人民医院神经外科,荆州434000

出　　处：《临床神经外科杂志》2017年第2期142-144,共3页Journal of Clinical Neurosurgery

摘　　要：目的探讨多囊肾合并颅内动脉瘤性蛛网膜下腔出血的临床特点及诊治方法。方法回顾性分析2例多囊肾合并颅内动脉瘤性蛛网膜下腔出血患者的临床资料,并复习国内外相关文献进行总结分析。结果 2例患者均有多囊肾、高血压和肾功能异常,以蛛网膜下腔出血发病。患者DSA检查为前交通动脉瘤,经颅内动脉瘤栓塞术治疗,术后恢复良好,肾功能异常无进一步发展。结论对于有多囊肾及蛛网膜下腔出血家族史的患者需完善动脉瘤的筛查,如发现颅内动脉瘤,需根据肾功能情况积极予以合适的治疗处理方案。Objective To explore the treatment methods in patients with autosomal-dominant polycystic kidney disease （ADPKD） and intracranial aneurysm （ ICAN ）. Methods We made retrospective analysis of clinical data about two patients with ADPKD and aneurysmal subarachnoid hemorrhage, but also made review of domestic and overseas literature related with the two diseases. Results DSA and vascular embolization of ICAN were implementeded in the two patients, who recovered well after embolization surgery, and the renal function in whom did not get worse. Conclusions Screening for ICAN is needed for patients with family history of ADPKD and subarachnoid hemorrhage;if ICAN is found,the suitable treatment methods are needed to implement according to the renal function of patients.

关 键 词：颅内动脉瘤 蛛网膜下腔出血 常染色显性遗传多囊肾病 临床特点 

分 类 号：R651.1[医药卫生—外科学] R692.1[医药卫生—临床医学]