“三伏天”穴位贴敷治疗变应性鼻炎疗效观察  

Observations on the Efficacy of Dog Days' Acupoint Application in Treating Allergic Rhinitis

作　　者：张红丽[1] 赵铭辉[2] 胡烨涛 傅立新[2] ZHANG Hong-li ZHAO Ming-hui HU Ye-tao FU Li-xin(xi＇an Medical College Second Hospitalian 710038,China Tianjin University of Traditional Chinese Medicine First Hospital, Tianjin 300193,China Tianjin University of Traditional Chinese Medicine First Hospital, Tianjin 300073,China)

机构地区：[1]西安医学院第二附属医院,西安710038 [2]天津中医药大学第一附属医院,天津300193 [3]天津中医药大学,天津300073

出　　处：《上海针灸杂志》2017年第5期588-593,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：天津市中医药管理局项目(13077)

摘　　要：目的观察"三伏天"穴位贴敷治疗变应性鼻炎的临床疗效并评价其安全性。方法将249例患者随机分为三伏贴组166例和安慰剂组83例。两组于三伏天初、中、末伏的第1天开始治疗,三伏贴组采用中药穴位贴敷;安慰剂组采用非药物成分的安慰剂穴位贴敷。观察两组治疗前后及随访期的症状积分、体征积分、VAS评分变化,复发情况,并评价穴位贴敷的临床疗效及安全性。结果治疗组总有效率为68.9%,安慰剂组为44.4%,三伏贴组近期疗效明显优于安慰剂组(P<0.01)。随访半年、1年后三伏贴组总有效率分别为89.4%、90.7%,安慰剂组为4.9%、1.2%,三伏贴组远期疗效明显优于安慰剂组(P<0.01)。三伏贴组治疗后及两随访期症状积分、体征积分、VAS评分均明显低于治疗前(P<0.01),而安慰剂组仅治疗后症状积分、体征积分、VAS评分与治疗前比较,差异具有统计学意义(P<0.01)。两组不同时间症状积分、体征积分、VAS评分比较,差异具有统计学意义(P<0.01)。三伏贴组不良反应发生率为4.3%,安慰剂组不良反应发生率为2.5%,两组比较差异无统计学意义(P>0.05)。两组贴敷不适感VAS评分比较,差异无统计学意义(P>0.05)。三伏贴组随访半年复发率为46.6%,1年复发率为62.1%;安慰剂为85.2%和95.1%,两组比较差异有统计学意义(P<0.01)。结论 "三伏天"穴位贴敷治疗变应性鼻炎近远期疗效较好,且复发率低,安全性良好。Objective To investigate the clinical efficacy of dog days＆#39; acupoint application in treating allergic rhinitis and assess its safety.Methods Two hundred and forty-nine patients were randomly allocated to a dog days＆#39; acupoint application group of 166 cases and a placebo group of 83 cases. The two groups were received treatment at the first day of the first, second and last periods of the hot season The dog days＆#39; acupoint application group received acupoint application of Chinese herbal medicine and the placebo group, acupoint application of non-medicinal placebo. In the two groups, the symptoms and signs were scored and the VAS score was recorded before and after treatment and during the follow-up period, and adverse reactions and relapses were observed and the clinical therapeutic effect of acupoint application and its safety were assessed after treatment and during the follow-up period.Results The total efficacy rate was 69.8% in the dog days＆#39; acupoint application group and 44.4% in the placebo group. The therapeutic effect was significantly better in the dog days＆#39; acupoint application group than in the placebo group （P〈0.01）. The totalefficacy rate was 89.4% at the 6-month follow-up and 90.7% at the 12-month follow-up in the dog days＆#39; acupoint application group and 4.9% and 1.2% in the placebo group. The long-term therapeutic effect was significantly better in the dog days＆#39; acupoint application group than in the placebo group （P〈0.01）. In the dog days＆#39; acupoint application group, the symptom score, the sign score and the VAS score were significantly lower after treatment and during the follow-up period than before treatment （bothP〈0.01）. In the placebo group, those scores only had significant pre-/post-treatment differences （P〈0.01）. There were statistically significant differences in the symptom score, the sign score and the VAS score between the two groups at different times. The adverse reaction rate was 4.3% in the dog days＆#39; acupo

关 键 词：变应性鼻炎 穴位贴敷法 穴位疗法 VAS评分 症状评分 体征评分 不良反应 复发率 

分 类 号：R246.8[医药卫生—针灸推拿学]