湖北省2010-2014年新报告HIV感染者/艾滋病患者新发感染状况分析  

New infection status of newly reported HIV infectors/AIDS patients in Hubei Province,2010-2014

作　　者：彭庭海[1] 彭国平[1] 阳凯[1] 陈慧萍[1] 蒋洪林[1] 汤恒[1] 刘聪[1] 郭萌[1] 

机构地区：[1]湖北省疾病预防控制中心,湖北武汉430079

出　　处：《实用预防医学》2017年第6期657-661,共5页Practical Preventive Medicine

基　　金：湖北省科技计划项目(2012DCA14001)

摘　　要：目的了解湖北省新报告HIV感染者/艾滋病患者(HIV/AIDS)新发感染状况。方法收集2010-2014年湖北省新报告HIV/AIDS信息及其中符合BED检测的HIV感染者首次HIV-1抗体确证阳性样本,进行BED检测,计算新报告HIV/AIDS新发感染比例;分层分析不同社会人口学特征、不同传播途径和不同样本来源新发感染的影响因素。结果同性、异性和注射吸毒及其他传播途径的HIV/AIDS中新发感染比例分别为31.47%、15.76%和14.10%,不同传播途径间差异有统计学意义(P<0.001);新报告HIV/AIDS中,与>50岁的相比,≤30岁(OR=1.284,95%CI:1.065~1.549,P=0.009)的更可能是新发感染;与农民及民工相比,商业服务、学生和干部职员(OR=1.412~2.616,P=0.034~<0.001)更可能是新发感染;与其他就诊者检测相比,通过检测咨询、MSM(男男同性)干预、专题调查、阳性配偶和性伴、羁押人员、无偿献血人员和性病门诊检测(OR=1.559~2.576,P=0.004~<0.001)发现的更可能是新发感染。结论 2010-2014年湖北省新报告HIV/AIDS中MSM的新发感染比例最高;应进一步发挥医疗机构和非政府组织作用,促进高危人群早检测,减少二代传播。Objective To investigate the new infection status of newly reported HIV infectors/AIDS patients in Hubei Province. Methods We collected the information of new reported HIV/AIDS cases in Hubei Province from 2010 to 2014 and screened the samples of HIV infectors with the firstly confirmed diagnosis of HIV- 1 antibody positive for BED assay to identify new infection. The proportions of new HIV/AIDS infections among different populations were calculated, and a stratified analysis method was used to analyze the factors affecting the new HIV/AIDS infections with respect to demographic characteristics, transmission routes and sample sources. Results The proportions of the new HIV/AIDS infections with homosexual, heterosexual as well as injection drug abuse and other transmission routes were 31.47%, 15.76% and 14.10% respectively, showing statistically significant differ- ences （ P〈0. 001）. Compared with the patients aged 〉 50 years, the ones aged ~ 30 years were more likely to be new infectors （ OR = 1.284, 95%（CI： 1.065 - 1. 549, P = 0. 009 ）. Compared with farmers and migrant workers, the commercial service clerks, young students and cadre staff were more likely to be new infectors （OR= 1.412-2.616,P= 0.034-〈0.001 ）. Compared with the patients identified by hospitals, the new HIV/AIDS infections were more likely to be found through voluntary counseling and tes- ting, MSM intervention, project-based surveillance, HIV positive spouses, sexual partners, custody personnel, voluntary blood donators and STD clinics （OR= 1.559-2.576,P=0.004-〈0.001 ）. Conclusions The new infection proportion in the newly reported HIV infectors/AIDS patients in Hubei Province in 2010-2014 is the highest among MSM . Medical institutions and non- governmental organizations should pay a bigger role in promoting HIV testing in high-risk groups and reduce the secondary transmission.

关 键 词：新报告HIV感染者/艾滋病患者 新发感染 BGD检测 

分 类 号：R512.91[医药卫生—内科学]