2型糖尿病患者应用益气育阴汤辅助治疗疗效及不良反应分析  

Analysis of the Curative Effect and Adverse Reaction of Qi Nourishing Yin Decoction for the Treatment of Patients With Type 2 Diabetes

作　　者：毛奇[1] MAO Qi(Endocrine Department, The Second Affiliated Hospital of Guiyang College of Traditional Chinese Medicine, Guiyang Guizhou 550003, Chin)

机构地区：[1]贵阳中医学院第二附属医院内分泌科,贵州贵阳550003

出　　处：《中国卫生标准管理》2017年第9期96-98,共3页China Health Standard Management

摘　　要：目的探讨益气育阴汤辅助治疗对2型糖尿病患者临床炎症状态、临床症状、生活质量及临床生化指标的影响。方法 180例诊断为2型糖尿病患者随机分为对照组与治疗组,每组各90例。对照组采用二甲双胍与地特胰岛素治疗,并加以饮食干预;治疗组在对照组治疗基础上加益气育阴汤治疗。检测两组治疗前、后血糖水平、炎症状态、临床症状积分及生活质量,并统计两组临床疗效及不良反应。结果治疗后,两组FBG、Hb A1c水平、炎症指标水平、中医证候积分低于治疗前,且治疗组低于对照组,P<0.05;且治疗组患者临床治疗总有效率95.56%,高于对照组72.22%,差异具有统计学意义(χ~2=18.81,P<0.05);治疗组不良反应率低于对照组,P<0.05。结论采用益气育阴汤联合二甲双胍与地特胰岛素治疗2型糖尿病者效果显著,且不良反应少,可有利于提高患者生活质量。Objective To investigate Qi Nourishing Yin Decoction therapy on clinical inflammatory status in patients with type 2 diabetes clinical symptoms, affecting the quality of life and clinical parameters. Methods 180 cases diagnosed with type 2 diabetes were randomly divided into control group and treatment group, 90 cases in each group. The use of metformin and extra insulin therapy, and control diet intervention; treatment group was in the control treatment with Invigorating Qi Nourishing Yin Decoction based on the treatment group. Two groups were detected before treatment, after the blood glucose level, inflammatory status, clinical symptom score and quality of life, and the statistics of clinical efficacy and adverse reactions of two groups. Results After treatment, two groups of FBG, HbAlc level, the level of inflammation index, TCM syndrome score was significantly lower than that before treatment, and the treatment group was significantly lower than the control group, treatment group （P 〈 0.05）. And the clinical treatment of patients with total efficiency of 95.56%, was significantly higher than the control group 72.22%, the difference was statistically significant （χ2=18.81, P 〈 0.05）. The adverse reaction rate of the treatment group was significantly lower than the control group （P 〈 0.05）. Conclusion Qi Nourishing Yin Decoction combined with metformin with insulin detemir therapy in type 2 diabetes has significant effect, and less adverse reaction, can help to improve the quality of life of patients.

关 键 词：益气育阴汤 二甲双胍 2型糖尿病 不良反应 

分 类 号：R259[医药卫生—中西医结合]