丝素蛋白/琼脂糖水凝胶的制备及性能研究  

Research on the Preparation and Property of Silk Fibroin/Agarose Gel

作　　者：陈思皓 舒浩[1] 刘祖兰[1] 李智[1] 代方银[1,2] 

机构地区：[1]重庆市生物质纤维材料与现代纺织工程技术研究中心西南大学纺织服装学院,重庆400716 [2]农业部蚕桑生物学与遗传育种重点实验室西南大学生物技术学院,重庆400716

出　　处：《蚕学通讯》2016年第4期5-8,共4页Newsletter of Sericultural Science

基　　金：863计划项目(2013AA102507);现代农业产业技术体系项目(CARS-22)

摘　　要：本研究利用丝素蛋白与不同浓度的琼脂糖混合的方法,制备成丝素蛋白/琼脂糖混合水凝胶,这种多孔结构的水凝胶,硬度最高可达1 050g,吸水溶胀率可高达700%,表明琼脂糖/丝素蛋白混合水凝胶具有良好的结构和力学性能,可以用于载药、皮肤敷料、骨组织再生等领域的进一步研究。In this research, the silk fibroin/agarose gel was produced based on the method that mixed the Silk fibroin with the agarose with varied concentration. This kind of hydrogel with the vesicular structure has the hardness up to 1 050g, the swelling rate as high as 700 % , which suggest that the hydrogel of silk fibroin/agarose has an excellent structure and me-chanical property. These results showed that the produced hydrogel owns the potential for further research on drug loading, skin dressing and bone regeneration, etc.

关 键 词：丝素蛋白 琼脂糖 混合水凝胶 力学性能 

分 类 号：TQ427.26[化学工程] R318.08[医药卫生—生物医学工程]