昆虫基因组及数据库研究进展  

The progress of insect genomic research and the gene database

作　　者：尹传林[1] 李美珍[1] 贺康[1] 丁思敏[1] 郭殿豪 席羽[1] 李飞[1] 

机构地区：[1]浙江大学昆虫科学研究所,杭州310058

出　　处：《环境昆虫学报》2017年第1期1-18,共18页Journal of Environmental Entomology

基　　金：国家重点研发计划"主要入侵生物的生物学特性分析"重大课题(2016YFC1200602)

摘　　要：基因组序列为昆虫分子生物学研究提供丰富的数据资源,推动系统生物学在古老的昆虫学中蓬勃发展。昆虫基因组学研究已经成为当前的研究热点,目前在NCBI登录注册的昆虫基因组测序计划有494项,其中已提交原始测序数据的昆虫有225种,完成基因组拼接的有215种,具有基因注释的有65种,公开发表的昆虫基因组有43篇。本文综述了测序技术发展的历史及其对昆虫基因组研究的推动作用、昆虫基因组的组装和注释及其存在的问题、昆虫基因组测序进展、昆虫基因组数据库的发展及基因数据挖掘利用的基本思路和对策,以及昆虫基因大数据在害虫防治和资源昆虫利用中的应用前景。With huge amount of insect genome sequencing data was generated, entomology has entered a new era of systematic biology. Up to now, 467 insect genome projects have been registered on NCBI, among which 225 have submitted with sequencing raw reads, 215 have been assemblied, 65 have been annotated and 43 have been published. Here, we reviewed the development of different sequence technologies, methods and problems of genome assembly, genome annotation and analysis, and important achievements in the field of insect genome projects. In addition, we summarized the development of insect genome databases. Insect genomics is now a hotspot of scientific study, which has wide applications in pest control and utilization of the resource insects.

关 键 词：昆虫基因组 组装与注释 数据挖掘与分析 基因组数据库 害虫防治 资源昆虫利用 

分 类 号：Q963[生物学—昆虫学] S43[农业科学—农业昆虫与害虫防治]