手足口病患儿血清免疫球蛋白A水平分析  

Analysis of serum immunoglobulin A （IgA） level in children with hand-foot-mouth disease

作　　者：夏婷婷[1] 

机构地区：[1]泰州市人民医院检验科,江苏泰州225300

出　　处：《临床研究》2017年第4期187-188,共2页Clinical Research

摘　　要：目的探讨在手足口病患儿诊治中实施血清免疫球蛋白A（IgA）水平监测的临床意义.方法选取2015年11月至2016年11月本院收治的60例手足口病患儿（手足口病组）及60例健康体检儿童（健康组）进行研究,对所有儿童均实施IgA水平监测,了解两组儿童IgA水平及阳性检测结果,并分析手足口病组IgA阳性及阴性儿童的病情状况.结果手足口病组患儿IgA水平与健康组相比明显较低,差异有统计学意义（P〈0.05）.手足口病组患儿IgA阳性率与健康组相比明显较高,差异具有统计学意义（P〈0.05）.手足口病组中IgA阳性患儿的发热时间、病程与IgA阴性患儿相比明显更长,差异具有统计学意义（P〈0.05）.结论手足口病患儿实施IgA水平监测可及时了解患儿的病情状况,有效辅助患儿的疾病诊治.Objective To investigate the clinical significance of serum immunoglobulin A （IgA） monitoring in the diagnosis and treatment of children with hand-foot-mouth disease. Methods Sixty cases of children with hand-foot-mouth disease in our hospital from November 2015 to November 2016 were selected as hand -foot - mouth disease group, and 60 cases of healthy children in same period were selected as healthy group, then the IgA levels monitoring were enforced between the two groups to analyze the IgA levels and positive test results in the two groups, and explore the positive and negative children＇s illness state in hand-foot-mouth disease group. Results The level of IgA in hand-foot-mouth disease group was lower than that in healthy group,the difference was statistically significant （P〈0.05）, and the positive rate of IgA in hand -foot-mouth disease group was significantly higher than that in the healthy group （P〈0.05）. In hand-foot-mouth disease group, the onset time and course in IgA positive children were significantly longer than those in IgA negative children （P〈0.05）. Conclusion The monitoring of serum IgA in children with hand-foot-mouth disease can keep abreast of the condition of children and effectively assist the diagnosis and treatment of children.

关 键 词：手足口病 诊断 血清免疫球蛋白A 

分 类 号：R725.1[医药卫生—儿科]