脑电双频指数与主观量表评价早期镇静深度相关性的Meta分析  

Correlation between bispectral index monitor and subjective scale in assessing the depth of sedation of mechanically ventilated patients:a meta-analysis

作　　者：王助衡[1] 陈晗[2] 周建新[2] 

机构地区：[1]首都医科大学大兴教学医院重症医学科,北京102600 [2]首都医科大学附属北京天坛医院重症医学科,北京100050

出　　处：《中国循证医学杂志》2017年第5期544-549,共6页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价基于Spearman相关系数的脑电双频指数(bispectral index,BIS)与Richmond镇静躁动评分(Richmond agitation sedation scale,RASS)和镇静-躁动评分(sedation-agitation scale,SAS)的相关性。方法计算机检索PubMed、EMbase、Web ofScience、The Cochrane Library(2016年7期)、CNKI、VIP、WanFang Data和CBM数据库,检索时限均为从建库至2016年7月,查找关于BIS与RASS和(或)SAS评价ICU机械通气早期患者镇静深度的研究。由两位评价者独立筛选文献、提取资料、评价纳入研究的偏倚风险后,采用Comprehensive Meta Analysis 3.0软件进行Meta分析。结果共纳入12个研究,包括397例患者。Meta分析结果显示:BIS与RASS和SAS的相关系数分别为[0.742,95%CI(0.678,0.795)]和[0.605,95%CI(0.517,0.681)]。结论BIS与RASS和SAS具有良好的相关性,可能为评价ICU机械通气早期患者镇静深度的提供更多选择。Objective To assess the correlation between bispectral index （BIS） and richmond agitation sedation scale （RASS） and sedation-agitation scale （SAS） through the spearman correlation coefficient by systematic review. Methods Databases including PubMed, EMbase, Web of Science, The Cochrane Library （Issue 7, 2016）, CNKI, VIP, WanFang Data and CBM were searched from inception to July 2016 to collect literature on the correlation between BIS and RASS and SAS. The studies were screened according to the inclusion and exclusion criteria. After extracting data and assessing the quality of the included studies, meta-analysis was conducted using Comprehensive Meta Analysis 3.0 software. Results A total of 12 studies involving 397 patients were included. BIS was positively correlated with RASS score and SAS, and the summary correlation coefficient was 0.742 with 95% CI 0.678 to 0.795 and 0.605 with 95% CI 0.517 to 0.681, respectively. Conclusion BIS has a good correlation with RASS and SAS, which will provide more options for assessing sedation of patients with mechanical ventilation in ICU.

关 键 词：脑电双频指数 机械通气 镇静 Richmond镇静躁动评分 镇静-躁动评分 META分析 

分 类 号：R614[医药卫生—麻醉学]